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15(S)-HETE
Item number: Cay34720-25
15(S)-HETE is an active metabolite of arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607). It is formed via oxidation of arachidonic acid by 15-lipoxygenase 2 (15-LO-2) in macrophages, as well as the prostate, lung, and skin, but also by 15-LO-1 in airway epithelial cells, eosinophils, and reticulocytes....
| Keywords: | 15S-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 54845-95-3 |
| MW: | 320.5 D |
From 54.00€
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Pentacosanoic Acid methyl ester
Item number: Cay10006451-100
Long chain saturated fatty acids and their esters are common components of plant lipids. Pentacosanoic acid methyl ester is the methyl ester of the 25-carbon, fully saturated fatty acid pentacosanoic acid. This product is designed to be used as a standard in total fatty acid analysis.Formal Name: pentacosanoic acid,...
| Keywords: | Methyl Pentacosanoate, pentacosanoic acid, methyl ester |
| Application: | Standard |
| CAS | 55373-89-2 |
| MW: | 396.7 D |
From 91.00€
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JTE-013
Item number: Cay10009458-10
JTE-013 is a sphingosine-1-phosphate receptor 2 (S1P2) and S1P4 antagonist (IC50s = 17 and 237 nM, respectively). It is selective for S1P2 over S1P1 and S1P3 (IC50s = >10 µM for both). JTE-013 (1 and 10 µM) reverses S1P-induced inhibition of human umbilical vein endothelial cell (HUVEC) and smooth muscle cell (SMC)...
| Keywords: | N-(2,6-dichloro-4-pyridinyl)-2-[1,3-dimethyl-4-(1-methylethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]-hydrazinecarboxamide |
| Application: | S1P2 receptor antagonist |
| CAS | 383150-41-2 |
| MW: | 408.3 D |
From 36.00€
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(±)17(18)-EpETE
Item number: Cay50861-500
(±)17(18)-EpETE is biosynthesized by the stereospecific epoxidation of the omega-3 bond of EPA. (±)17(18)-EpETE at 100 nM was found to be a potent and selective activator of large-conductance calcium-activated potassium channels (KCa1.1/BK) in vascular smooth muscle cells. It is possible that some of the physiologic...
| Keywords: | (±)17,18-EEQ, (±)17,18-epoxy Eicosatetraenoic Acid, (±)17,18-epoxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| MW: | 318.5 D |
From 78.00€
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Tauro-omega-muricholic Acid (sodium salt)
Item number: Cay28842-1
Tauro-omega-muricholic acid is a taurine-conjugated form of the secondary bile acid omega-muricholic acid (Cay-20292). Hepatic levels of tauro-omega-muricholic acid are decreased in mice following a diet supplemented with cholic, deoxycholic, chenodeoxycholic, or ursodeoxycholic acid and in a high-fat diet-induced...
| Keywords: | TOMCA, T-omega-MCA,... |
| Application: | Taurine-conjugated, secondary bile acid |
| CAS | 2456348-84-6 |
| MW: | 537.7 D |
From 263.00€
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Palmitoleic Acid
Item number: Cay10009871-100
Palmitoleic acid is an omega-7 monounsaturated fatty acid that has been found in macadamia and sea buckthorn oils. It increases basal and insulin-stimulated glucose uptake and glucose transporter 4 (Glut4) protein levels in 3T3-L1 adipocytes when used at a concentration of 200 µM. Ex vivo, palmitoleic acid (300...
| Keywords: | (9Z)-Hexadecenoic Acid, cis-Palmitoleic Acid, C16:1 n-7, C16:1(9Z), (9Z)-hexadecenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 373-49-9 |
| MW: | 254.4 D |
From 35.00€
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Calicheamicin gamma1
Item number: Cay40830-1
Calicheamicin gamma1 is a polyketide synthase-derived enediyne that has been found in M. echinospora. It is composed of carbohydrate and aromatic moieties, which bind to the minor groove in DNA, and a warhead moiety that aromatizes and oxidatively induces double-stranded DNA scission in cell-free assays.Formal Name:...
| Keywords: | Calicheamicin gamma1I,... |
| Application: | Polyketide enediyne, potent antitumor agent |
| CAS | 108212-75-5 |
| MW: | 1368.3 D |
From 187.00€
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4A3-SCC-10
Item number: Cay41276-10
4A3-SCC-10 is a disulfide bond-containing biodegradable ionizable cationic lipid (pKa = 6.22) that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo. LNPs containing 4A3-SCC-10 and encapsulating a Cy5-RNA reporter have improved endosomal escape ability over...
| Keywords: | ((methylazanediyl)bis(propane-3,1-diyl))bis(8,14-dioxo-7,15-dioxa-3,4,18,19-tetrathia-11-azahenicosane-11,1,21-triyl)... |
| Application: | Disulfide bond-containing biodegradable ionizable cationic lipid, LNP formation |
| MW: | 1948.1 D |
From 62.00€
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Ciclesonide
Item number: LKT-C324091.100
Ciclesonide is an anti-inflammatory corticosteroid. Its active metabolite and several ciclesonide-acetal derivatives have been found to block RNA replication of the SARS-Cov-2 virus. Ciclesonide also inhibits lung cancer stem cells through Hedgehog signaling-mediated SOX2 regulation. Solubility: Insoluble in water....
| Keywords: | Alvesco, Omnaris, Zetonna, RPR251526, (R)-11beta,16alpha,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal... |
| Application: | Corticosteroid |
| CAS | 126544-47-6 |
| MW: | 540.7 D |
From 138.00€
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Lauroylsarcosine (sodium salt)
Item number: Cay33718-100
Lauroylsarcosine is a fatty acid amide and detergent. It has been used to solubilize recombinant and membrane proteins.Formal Name: N-methyl-N-(1-oxododecyl)-glycine, monosodium salt. CAS Number: 137-16-6. Synonyms: Sarkosyl, SDDS, Sodium Lauroyl Sarcosinate, Sodium N-dodecanoyl Sarcosinate. Molecular Formula:...
| Keywords: | Sarkosyl, SDDS, Sodium Lauroyl Sarcosinate, Sodium N-dodecanoyl Sarcosinate, N-methyl-N-(1-oxododecyl)-glycine, monosodium... |
| Application: | Fatty acid amide, detergent |
| CAS | 137-16-6 |
| MW: | 293.4 D |
From 52.00€
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2-Arachidonoyl Glycerol-d8
Item number: Cay362160-100
2-Arachidonoyl glycerol-d8 (2-AG-d8) is intended for use as an internal standard for the quantification of 2-AG (Cay-62160) by GC- or LC-MS. 2-AG is an endogenous agonist of the CB1 receptor. Unlike anandamide, 2-AG is present at relatively high levels in the central nervous system, it is the most abundant molecular...
| Keywords: | 2-AG-d8, 5Z,8Z,11Z,14Z-eicosatetraenoic-5,6,8,9,11,12,14,15-d8 acid, 2-glyceryl ester |
| Application: | Standard |
| CAS | 924894-97-3 |
| MW: | 386.6 D |
From 103.00€
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Palmitic Acid Alkyne
Item number: Cay13266-1
Protein S-palmitoylation is the post-translational acylation of proteins and serves to regulate localization, stability, and interaction with associates and substrates. Palmitic acid alkyne is a form of palmitic acid (Cay-10006627) with an omega-terminal alkyne. The terminal alkyne group can be used in linking...
| Keywords: | Alk-14, Click Tag(TM) Palmitic Acid Alkyne, 15-hexadecynoic acid |
| Application: | Lipid bioconjugation |
| CAS | 99208-90-9 |
| MW: | 252.4 D |
From 87.00€
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