Lipids

Lipids are small, organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids. Lipids are the main structural component of biological membranes of all cells. As such, bacterial lipid structures and glycolipids can serve as pathogen-associated molecular patterns (PAMPs) and are recognized by the human immune system. Various lipids and lipid complexes of bacterial origin are therefore used as immunostimulants.

Lipids are small,  organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids.... read more »
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Lipids

Lipids are small, organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids. Lipids are the main structural component of biological membranes of all cells. As such, bacterial lipid structures and glycolipids can serve as pathogen-associated molecular patterns (PAMPs) and are recognized by the human immune system. Various lipids and lipid complexes of bacterial origin are therefore used as immunostimulants.

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n-Decyl-beta-D-Glucopyranoside
n-Decyl-beta-D-Glucopyranoside

Item number: Cay42722-1

n-Decyl-beta-D-glucopyranoside is a nonionic alkyl glucoside chiral surfactant with a critical micelle concentration (CMC) value of 0. mM. It has been used to solubilize membrane proteins. Formulations containing n-decyl-beta-D-glucopyranoside are associated with allergic contact dermatitis.. Solulibility: DMSO:...
Keywords: C10betaGlc, Decyl Glucoside, decyl, beta-D-glucopyranoside
Application: Nonionic alkyl glucoside chiral surfactant
CAS 58846-77-8
MW: 320.43 D
From 177.00€ *
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Lipid TG4C
Lipid TG4C

Item number: Cay42941-1

Lipid TG4C is an ionizable cationic glycerolipid (pKa = 6.71) that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vivo. LNPs containing lipid TG4C and encapsulating mRNA encoding human erythropoietin (EPO) increase serum EPO levels in mice. Nebulized administration of LNPs...
Keywords: hexanedioic acid, 1,1'-[2-[4-(dimethylamino)-1-oxobutoxy]-1,3-propanediyl] 6,6'-bis(1-octylnonyl) ester
Application: Ionizable cationic glycerolipid, LNP formation
CAS 3028336-07-1
MW: 938.43 D
From 102.00€ *
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Triamcinolone hexacetonide
Triamcinolone hexacetonide

Item number: Cay42600-100

Triamcinolone hexacetonide is a synthetic corticosteroid and prodrug form of triamcinolone acetonide (Cay-18026). Intra-articular administration of triamcinolone hexacetonide decreases joint swelling in a rabbit model of adjuvant-induced arthritis. Formulations containing triamcinolone hexacetonide have been used in...
Keywords: 21-(3,3-dimethyl-1-oxobutoxy)-9-fluoro-11beta-hydroxy-16a,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione
Application: Triamcinolone acetonide prodrug, synthetic corticosteroid, glucocorticoid receptor agonist
CAS 5611-51-8
MW: 532.64 D
From 109.00€ *
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LipidLaunch(TM) Ionizable Lipid LNP Screening Set
LipidLaunch(TM) Ionizable Lipid LNP Screening Set

Item number: Cay42832-1

The LipidLaunchTM Ionizable Lipid LNP Screening Set includes 12 ionizable cationic and cationic lipids to screen for use in lipid nanoparticle (LNP) formulations. The lipids are formulated at 10 mg/ml in ethanol for ease of addition to lipid mixes for LNP formulation. Lipids selected for this screening set include...
Application: LNP formulation cationic / ionizable cationic lipid screening set
1,220.00€ *
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514O6,10
514O6,10

Item number: Cay42917-1

514O6,10 is an ionizable cationic lipid that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vivo. LNPs containing 514O6,10 and encapsulating an mRNA reporter traffic to the spleen, lungs, and liver in mice.. Solulibility: Ethanol: Soluble: =10 mg/ml: .
Keywords: bis(2-hexyldecyl) 7,11-diethyl-4,14-bis(3-((2-hexyldecyl)oxy)-3-oxopropyl)-4,7,11,14-tetraazaheptadecanedioate
Application: Ionizable cationic lipid, LNP formation
CAS 2863553-06-2
MW: 1402.3 D
From 68.00€ *
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C16 Ganglioside GM1 (d18:1/16:0) (ammonium salt)
C16 Ganglioside GM1 (d18:1/16:0) (ammonium salt)

Item number: Cay42979-100

Ganglioside GM1 is a monosialylated ganglioside and the prototypic ganglioside for those containing one sialic acid residue. C16 Ganglioside GM1 is a monosialylated ganglioside that contains a 16-carbon saturated acyl chain. It has been found in the brain of wild-type mice and mice lacking the gene for...
Keywords: C16 GM1, N-Hexadecanoyl-monosialoganglioside GM1,...
Application: Monosialylated ganglioside
MW: 1535.82 D
384.00€ *
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C18 Ganglioside GM1 (d18:1/18:0) (ammonium salt)
C18 Ganglioside GM1 (d18:1/18:0) (ammonium salt)

Item number: Cay42980-100

Ganglioside GM1 is a monosialylated ganglioside and the prototypic ganglioside for those containing one sialic acid residue. C18 Ganglioside GM1 is found in the brain, primarily in the piriform cortex, amygdala nucleus, striatum, and hippocampal CA1 region. The ratio of C18 ganglioside GM1 (d20:1/18:0) to C18...
Keywords: C18 GM1, GM1 (18:1/18:0), GM1 (d18:1/C18:0), N-Octadecanoyl Monosialoganglioside GM1, N-Stearoyl Monosialoganglioside GM1,...
Application: Monosialylated ganglioside
CAS 1329115-44-7
MW: 1563.87 D
384.00€ *
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3-O-methyl Estradiol
3-O-methyl Estradiol

Item number: Cay42995-1

3-O-methyl Estradiol is a synthetic estrogen. It disrupts microtubule networks in V79 Chinese hamster cells (EC50 = 9 µM) and inhibits the proliferation of the same cells by 92% when used at a concentration of 20 µM. 3-O-methyl Estradiol (25 mg in a 0. ml solution, p.o.) decreases serum cholesterol levels and...
Keywords: 3-Methoxyestradiol, 3-O-methyl E2, Estradiol 3-methyl ether, NSC 58851, (17beta)-3-methoxy-estra-1,3,5(10)-trien-17-ol
Application: Synthetic estrogen
CAS 1035-77-4
MW: 286.42 D
From 42.00€ *
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4-Methylumbelliferyl-hexadecyloxy-beta-D-Glucopyranoside
4-Methylumbelliferyl-hexadecyloxy-beta-D-Glucopyranoside

Item number: Cay43067-1

4-Methylumbelliferyl-hexadecyloxy-beta-D-glucopyranoside is a fluorogenic substrate for beta-glucocerebrosidase (GBA1). It is selective for GBA1 over GBA2 and GBA3. Hydrolysis of 4-methylumbelliferyl-hexadecyloxy-beta-D-glucopyranoside by GBA1 releases the fluorescent moiety 4-MU, which displays an emission maximum...
Keywords: 4-Methylumbelliferyl-hexadecyloxy-beta-D-Glucoside, 4-MU-hexadecyloxy-beta-D-Glucopyranoside,...
Application: Fluorogenic beta-glucocerebrosidase substrate
MW: 562.74 D
343.00€ *
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Lipid PPz-2R1
Lipid PPz-2R1

Item number: Cay43160-10

Lipid PPz-2R1 is an ionizable cationic lipid that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo. LNPs containing lipid PPz-2R1 and encapsulating an mRNA reporter selectively accumulate in lungs over the heart, liver, spleen, and kidneys in mice. LNPs...
Keywords: piperazine-1,4-diylbis(hexane-6,1-diyl) bis(2-hexyldecanoate)
Application: Ionizable cationic lipidoid, LNP formation
CAS 2832061-40-0
MW: 763.29 D
From 109.00€ *
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DSPE-MPEG(5000)
DSPE-MPEG(5000)

Item number: Cay43359-10

DSPE-MPEG(5000) is a PEGylated form of 1,2-distearoyl-sn-glycero-3-PE (1,2-DSPE, Cay-15095). It has been used in the generation of lipid nanoparticles (LNPs) and liposomes for in vitro and in vivo two-photon bioimaging.. Solulibility: DMSO: Slightly soluble: 0.1-1 mg/ml: PBS (pH 7.2): Sparingly soluble: 1-10 mg/ml.
Keywords: 1,2-Distearoyl-sn-glycero-3-PE-methoxy-Polyethyleneglycol-5000, 1,2-Distearoyl-sn-glycero-3-Phosphoethanolamine-mPEG-5000,...
Application: PEGylated DSPE, LNP formation
CAS 156543-00-9
From 117.00€ *
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17(S)-HDHA serinol amide
17(S)-HDHA serinol amide

Item number: Cay9004368-100

17(S)-HDHA serinol amide is a derivative of 17(S)-HDHA (Cay-10009799).
Keywords: 17(S)-HDoHE serinol amide, 17(S)-hydroxy DHA serinol amide, 17(S)-hydroxy Docosahexaenoic Acid serinol amide,...
Application: 17(S)-hydroxy DHA derivative
MW: 417.6 D
From 103.00€ *
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