(±)8(9)-DiHET

(±)8(9)-DiHET
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay51351-25 25 µg -

6 - 10 business days*

135.00€
Cay51351-50 50 µg -

6 - 10 business days*

255.00€
Cay51351-100 100 µg -

6 - 10 business days*

481.00€
Cay51351-250 250 µg -

6 - 10 business days*

1,066.00€
 
(±)8(9)-DiHET is an oxylipin and a racemic mixture of the arachidonic acid metabolites... more
Product information "(±)8(9)-DiHET"
(±)8(9)-DiHET is an oxylipin and a racemic mixture of the arachidonic acid metabolites 8(S),9(R)-DiHET and 8(R),9(S)-DiHET. It is formed from arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607) via an (±)8(9)-EET (Cay-50351) intermediate by epoxide hydrolases. (±)8(9)-DiHET (1 µM) induces cAMP production in primary human coronary artery smooth muscle cells. Plasma levels of (±)8(9)-DiHET are increased in a mouse model of osteoarthritic pain induced by destabilization of the medial meniscus, an effect that can be reversed by the soluble epoxide hydrolase (sEH) inhibitor TPPU (Cay-11120). Spinal cord levels of (±)8(9)-DiHET are also increased in a rat model of surgically-induced acute spinal cord injury (SCI).Formal Name: (±)8,9-dihydroxy-5Z,11Z,14Z-eicosatrienoic acid. CAS Number: 192461-96-4. Synonyms: (±)8,9-DiHETrE. Molecular Formula: C20H34O4. Formula Weight: 338.5. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 50 mg/ml, DMSO: 50 mg/ml, Ethanol: 50 mg/ml, PBS pH 7.2: 1 mg/ml. SMILES: O[C@H](C/C=C\C/C=C\CCCCC)[C@@H](C/C=C\CCCC(O)=O)O. InChi Code: InChI=1S/C20H34O4/c1-2-3-4-5-6-7-8-9-12-15-18(21)19(22)16-13-10-11-14-17-20(23)24/h6-7,9-10,12-13,18-19,21-22H,2-5,8,11,14-17H2,1H3,(H,23,24)/b7-6-,12-9-,13-10-/t18-,19-/m1/s1. InChi Key: DCJBINATHQHPKO-CALMLMJYSA-N.
Keywords: (±)8,9-DiHETrE, (±)8,9-dihydroxy-5Z,11Z,14Z-eicosatrienoic acid
Supplier: Cayman Chemical
Supplier-Nr: 51351

Properties

Application: Bioactive lipid assays
MW: 338.5 D
Formula: C20H34O4
Purity: >98%
Format: Solution

Database Information

CAS : 192461-96-4| Matching products

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225, H319
P Phrases: P210, P233, P240, P241, P242, P243, P264, P280, P303+361+353, P305+351+338, P337+313, P370+378, P403+235, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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