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Epoxide hydrolases convert the EETs into vicinal diols, with the concurrent loss of much of their biological activity. The 8(S),9(R)-EET isomer is metabolized by platelet COX to form 8(S),9(R),11(R)-THETA, a trihydroxy fatty acid which may act as a renal vasoconstrictor. Formal Name: (±)8,9-dihydroxy-5Z,11Z,14Z-eicosatrienoic acid. CAS Number: 192461-96-4. Synonyms: (±)8,9-DiHETrE. Molecular Formula: C20H34O4. Formula Weight: 338.5. Purity: >98%. Formulation: A solution in ethanol. Solubility: DMF: 50 mg/ml, DMSO: 50 mg/ml, Ethanol: 50 mg/ml, PBS pH 7.2: 1 mg/ml. SMILES: O[C@H](C/C=C\C/C=C\CCCCC)[C@H](C/C=C\CCCC(O)=O)O. InChi Code: InChI=1S/C20H34O4/c1-2-3-4-5-6-7-8-9-12-15-18(21)19(22)16-13-10-11-14-17-20(23)24/h6-7,9-10,12-13,18-19,21-22H,2-5,8,11,14-17H2,1H3,(H,23,24)/b7-6-,12-9-,13-10-/t18-,19+/m1/s1/i1D3,2D2,3D2,4D2,5D2. InChi Key: DCJBINATHQHPKO-ZZMPYBMWSA-N.