7beta-hydroxy Cholesterol-d7

7beta-hydroxy Cholesterol-d7 is intended for use as an internal standard for the quantification of 7beta-hydroxy cholesterol by GC- or LC-MS. 7beta-hydroxy Cholesterol is an oxysterol formed by enzymatic and non-enzymatic oxidation of cholesterol. It is the primary oxysterol found in LDL and induces apoptosis and cell death of human umbilical vein endothelial cells (HUVECs) in vitro in a concentration-dependent manner. Increased plasma levels of 7beta-hydroxy cholesterol positively correlate with mortality in coronary heart disease in human males.Formal Name: (3beta,7beta)-cholest-5-ene-25,26,26,26,27,27,27-d7-3,7-diol. CAS Number: 349553-97-5. Molecular Formula: C27H39D7O2. Formula Weight: 409.7. Purity: >99% deuterated forms (d1-d7). Formulation: (Request formulation change), A solid. Solubility: DMF: 1 mg/ml, DMSO: 0.1 mg/ml, Ethanol: 20 mg/ml. SMILES: O[C@H](C1)CC[C@@]2(C)C1=C[C@H](O)[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@H](C)CCCC(C([2H])([2H])[2H])([2H])C([2H])([2H])[2H]. InChi Code: InChI=1S/C27H46O2/c1-17(2)7-6-8-18(3)21-9-10-22-25-23(12-14-27(21,22)5)26(4)13-11-20(28)15-19(26)16-24(25)29/h16-18,20-25,28-29H,6-15H2,1-5H3/t18-,20+,21-,22+,23+,24+,25+,26+,27-/m1/s1/i1D3,2D3,17D. InChi Key: OYXZMSRRJOYLLO-SVAMASIOSA-N.