(±)5(6)-DiHET

(±)5(6)-DiHET
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay51211-25 25 µg -

6 - 10 business days*

93.00€
Cay51211-50 50 µg -

6 - 10 business days*

177.00€
Cay51211-100 100 µg -

6 - 10 business days*

333.00€
Cay51211-250 250 µg -

6 - 10 business days*

740.00€
 
5(6)-DiHET is a fully racemic version of the enantiomeric forms biosynthesized from 5(6)-EET... more
Product information "(±)5(6)-DiHET"
5(6)-DiHET is a fully racemic version of the enantiomeric forms biosynthesized from 5(6)-EET (Cay-50211, Cay-10007260) by epoxide hydrolases. 5(6)-DiHET can be used to quantify 5(6)-EET due to the conversion of 5(6)-EET to 5(6)-delta-lactone in solution. 5(6)-DiHET activates large conductance calcium-activated potassium (BK) channels in smooth muscle cells from rat small coronary arteries. It is a substrate for sheep seminal vesicle COX, producing 5,6-dihydroxy prostaglandin E1 and F1alpha metabolites in vitro. 5(6)-DiHET levels decrease in plasma in a high-fat diet-induced rat model of hyperlipidemia. Formal Name: (±)5,6-dihydroxy-8Z,11Z,14Z-eicosatrienoic acid. CAS Number: 213382-49-1. Synonyms: (±)5,6-DiHETrE. Molecular Formula: C20H34O4. Formula Weight: 338.5. Purity: >95%. Formulation: A solution in ethanol. Solubility: DMF: >50 mg/ml (per Rao Maddipati), DMSO: >50 mg/ml (per Rao Maddipati), Ethanol: >50 mg/ml (per Rao Maddipati), PBS pH 7.2: >1 mg/ml (from 13(S)-HODE). SMILES: CCCCC/C=C\C/C=C\C/C=C\C[C@@H](O)[C@@H](O)CCCC(O)=O. InChi Code: InChI=1S/C20H34O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-15-18(21)19(22)16-14-17-20(23)24/h6-7,9-10,12-13,18-19,21-22H,2-5,8,11,14-17H2,1H3,(H,23,24)/b7-6-,10-9-,13-12-/t18-,19+/m1/s1. InChi Key: GFNYAPAJUNPMGH-GSKBNKFLSA-N.
Keywords: (±)5,6-DiHETrE, (±)5,6-dihydroxy-8Z,11Z,14Z-eicosatrienoic acid
Supplier: Cayman Chemical
Supplier-Nr: 51211

Properties

Application: Bioactive lipid assays
MW: 338.5 D
Formula: C20H34O4
Purity: >95%
Format: Solution

Database Information

CAS : 213382-49-1| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225
P Phrases: P210, P233, P240, P241, P242, P243, P280, P303+361+353, P370+378, P403+235, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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