4-Methylcatechol

4-Methylcatechol
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay36429-5 5 g -

6 - 10 business days*

39.00€
Cay36429-10 10 g -

6 - 10 business days*

69.00€
Cay36429-50 50 g -

6 - 10 business days*

152.00€
 
4-Methylcatechol is a methylcatechol with diverse biological activities and an active metabolite... more
Product information "4-Methylcatechol"
4-Methylcatechol is a methylcatechol with diverse biological activities and an active metabolite of the flavonoid quercetin (Cay-10005169). It is formed from quercetin by gut microbiota. 4-Methylcatechol inhibits migration of, and induces cell cycle arrest in the G2/M phase, production of reactive oxygen species (ROS), and apoptosis in, 1205Lu melanoma cells when used at concentrations of 10 and 25 µg/ml. It induces relaxation of isolated rat aortic rings and mesenteric arteries (EC50s = 49.1 and 21.2 µM, respectively) and reduces blood pressure in spontaneously hypertensive stroke-prone (SHRSP) rats.Formal Name: 4-methyl-1,2-benzenediol. CAS Number: 452-86-8. Synonyms: 1,2-Dihydroxy-4-methylbenzene, 3,4-Dihydroxytoluene, Homocatechol, 2-Hydroxy-4-methylphenol, 4-Methylpyrocatechol, NSC 17489, p-Methylcatechol. Molecular Formula: C7H8O2. Formula Weight: 124.1. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMF: 25 mg/ml, DMSO: 20 mg/ml, Ethanol: 3 mg/ml, PBS (pH 7.2): 5 mg/ml. SMILES: OC1=CC=C(C)C=C1O. InChi Code: InChI=1S/C7H8O2/c1-5-2-3-6(8)7(9)4-5/h2-4,8-9H,1H3. InChi Key: ZBCATMYQYDCTIZ-UHFFFAOYSA-N. Origin: Synthetic.
Keywords: p-Methylcatechol, 1,2-Dihydroxy-4-methylbenzene, 2-Hydroxy-4-methylphenol, 3,4-Dihydroxytoluene, 4-Methylpyrocatechol, Homocatechol, NSC 17489, 4-methyl-1,2-benzenediol
Supplier: Cayman Chemical
Supplier-Nr: 36429

Properties

Application: Bioactive methylcatechol, active quercetin metabolite
MW: 124.1 D
Formula: C7H8O2
Purity: >98%
Format: Solid

Database Information

CAS : 452-86-8| Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H315, H319, H335
P Phrases: P261, P264, P271, P280, P312, P321, P302+P352, P304+P340, P305+P351+P338, P332+P313, P337+P313, P362+P364, P405, P403+P233, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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