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4-hydroxy Tolbutamide is a cytochrome P450 2C8 (CYP2C8) and CYP2C9 metabolite of tolbutamide, a first-generation potassium channel blocker. Tolbutamide 4-hydroxylation is an often used probe reaction in the pharmaceutical industry for the characterization of CYP2C8 and CYP2C9 involvement in the metabolism of clinical drugs. Formal Name: N-[(butylamino)carbonyl]-4-(hydroxymethyl)-benzenesulfonamide. CAS Number: 5719-85-7. Molecular Formula: C12H18N2O4S. Formula Weight: 286.4. Purity: >98%. Formulation: A crystalline solid. lambdamax: 229 nm. SMILES: CCCCNC(=O)NS(=O)(=O)c1ccc(CO)cc1. InChi Code: InChI=1S/C12H18N2O4S/c1-2-3-8-13-12(16)14-19(17,18)11-6-4-10(9-15)5-7-11/h4-7,15H,2-3,8-9H2,1H3,(H2,13,14,16). InChi Key: SJRHYONYKZIRPM-UHFFFAOYSA-N.