17alpha-Estradiol

17alpha-Estradiol
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay20776-50 50 mg -

6 - 10 business days*

54.00€
Cay20776-100 100 mg -

6 - 10 business days*

102.00€
Cay20776-500 500 mg -

6 - 10 business days*

185.00€
Cay20776-1 1 g -

6 - 10 business days*

262.00€
 
17alpha-Estradiol is the natural optical isomer of 17beta-estradiol (Cay-10006315), the major... more
Product information "17alpha-Estradiol"
17alpha-Estradiol is the natural optical isomer of 17beta-estradiol (Cay-10006315), the major estrogen secreted by the premenopausal ovary. 17alpha-Estradiol is a less active isomer than its counterpart, displaying 100-fold lower estrogenic activity relative to 17beta-estradiol. It can inhibit 5alpha-reductase, which plays a role in regulating hair growth. 17alpha -estradiol is reported to activate the MAPK/ERK and PI3K-Akt signaling pathways via activation of the estrogen receptor-X and has been shown to be neuroprotective after an ischemic stroke and oxidative stress and in transgenic mice with Alzheimer's disease.Formal Name: (17alpha)-estra-1,3,5(10)-triene-3,17-diol. CAS Number: 57-91-0. Synonyms: Alfatradiol, alpha-Estradiol, 17-epi Estradiol, NSC 20293, 17alpha-Oestradiol. Molecular Formula: C18H24O2. Formula Weight: 272.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMSO: 20 mg/ml, DMSO:PBS (pH 7.2) (1:4): 0.2 mg/ml, Ethanol: 2.5 mg/ml. SMILES: O[C@@H]1CC[C@@]2([H])[C@]([C@]3([H])CC[C@@]21C)([H])CCC4=C3C=CC(O)=C4. InChi Code: InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17-,18+/m1/s1. InChi Key: VOXZDWNPVJITMN-SFFUCWETSA-N.
Keywords: 17-epi Estradiol, 17alpha-Oestradiol, Alfatradiol, NSC 20293, alpha-Estradiol, (17alpha)-estra-1,3,5(10)-triene-3,17-diol
Supplier: Cayman Chemical
Supplier-Nr: 20776

Properties

MW: 272.4 D
Formula: C18H24O2
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 57-91-0| Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H351, H360, H362
P Phrases: P201, P202, P260, P263, P264, P270, P280, P308+P313, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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