17(S)-HpDHA

17(S)-HpDHA is a mono-oxygenation product of docosahexaenoic acid in human whole blood, human leukocytes, human glial cells, and mouse brain. 17(S)-HpDHA is generally reduced to 17(S)-HDHA (Cay-10009799), a compound that serves as a precursor to 17(S)-resolvins. 17(S)-HDHA has been shown to inhibit TNF-alpha-induced interleukin-1beta expression in human glioma cells and inhibit TNF-alpha-induced leukocyte trafficking to the murine air pouch.Formal Name: 17S-hydroperoxy-4E,7Z,10Z,13Z,15Z,19Z-docosahexaenoic acid. CAS Number: 123673-33-6. Synonyms: 17(S)-hydroperoxy Docosahexaenoic Acid, 17(S)-HpDoHE. Molecular Formula: C22H32O4. Formula Weight: 360.5. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: Miscible, DMSO: Miscible, Ethanol: Miscible, PBS (pH 7.2): 0.8 mg/ml. SMILES: CC\C=C/C[C@H](OO)/C=C/C=C\C\C=C/C\C=C/C\C=C/CCC(O)=O. InChi Code: InChI=1S/C22H32O4/c1-2-3-15-18-21(26-25)19-16-13-11-9-7-5-4-6-8-10-12-14-17-20-22(23)24/h3,5-8,11-16,19,21,25H,2,4,9-10,17-18,20H2,1H3,(H,23,24)/b7-5-,8-6-,13-11-,14-12-,15-3-,19-16+. InChi Key: BNHQALRBDJVUQB-VIIQGJSXSA-N.