17-Octadecynoic Acid

17-Octadecynoic Acid (17-ODYA) is a fatty acid alkyne. It is a suicide inhibitor of leukotriene B4 20-hydroxylase and renal CYP450 omega-hydroxylase. 17-ODYA (10 µM) completely inhibits the bradykinin-dependent transport of sodium chloride in rat TALH cells. It has been used as a click chemistry probe for labeling palmitoylation substrates in vitro. It has also been used to study the formation of lipid droplets in live THP-1 macrophages and C. elegans.CAS Number: 34450-18-5. Synonyms: Alk-16, Click Tag(TM) 17-Octadecynoic Acid, FA 18:2, 17-ODYA. Molecular Formula: C18H32O2. Formula Weight: 280.5. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: 0.15 M Tris-HCl pH 8.5: 1 mg/ml, DMF: 10 mg/ml, DMSO: 1 mg/ml, Ethanol: 10 mg/ml, PBS pH 7.2: <1Insoluble. SMILES: CCCCCCCCCCCCCCCCCC(=O)O. InChi Code: InChI=1S/C18H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h1H,3-17H2,(H,19,20). InChi Key: DZIILFGADWDKMF-UHFFFAOYSA-N.