15(S)-Latanoprost

15(S)-Latanoprost
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay16818-1 1 mg -

6 - 10 business days*

104.00€
Cay16818-5 5 mg -

6 - 10 business days*

463.00€
Cay16818-10 10 mg -

6 - 10 business days*

819.00€
Cay16818-50 50 mg -

6 - 10 business days*

2,048.00€
 
15(S)-Latanoprost is an analog of latanoprost in which the hydroxyl at carbon 15 is inverted... more
Product information "15(S)-Latanoprost"
15(S)-Latanoprost is an analog of latanoprost in which the hydroxyl at carbon 15 is inverted relative to latanoprost. The IC50 values for the free acid forms of latanoprost and 15(S)-latanoprost were determined to be 3.6 nM and 24 nM, respectively, in a FP receptor binding assay using the cat iris sphincter muscle. A 3 µg dose of 15(S)-latanoprost caused a 1 mmHg reduction of IOP in normotensive cynomolgus monkeys. 15(S)-Latanoprost is a potential impurity in most commercial preparations of the latanoprost bulk drug product.Formal Name: (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3S)-3-hydroxy-5-phenylpentyl]cyclopentyl]-5-heptenoic acid, 1-methylethyl ester. CAS Number: 145773-22-4. Synonyms: 15-epi Latanoprost. Molecular Formula: C26H40O5. Formula Weight: 432.6. Purity: >98%. Formulation: (Request formulation change), A solution in methyl acetate. Solubility: DMF: 100 mg/ml, DMSO: 100 mg/ml, DMSO:PBS (1:12): 80 µg/ml, Ethanol: 100 mg/ml. SMILES: O[C@@H]1[C@H](C/C=C\CCCC(OC(C)C)=O)[C@@H](CC[C@H](O)CCC2=CC=CC=C2)[C@H](O)C1. InChi Code: InChI=1S/C26H40O5/c1-19(2)31-26(30)13-9-4-3-8-12-22-23(25(29)18-24(22)28)17-16-21(27)15-14-20-10-6-5-7-11-20/h3,5-8,10-11,19,21-25,27-29H,4,9,12-18H2,1-2H3/b8-3-/t21-,22-,23-,24+,25-/m1/s1. InChi Key: GGXICVAJURFBLW-SCTZCWPJSA-N.
Keywords: 15-epi Latanoprost, 9alpha,11alpha,15S-trihydroxy-17-phenyl-18,19,20-trinor-prost-5Z-en-1-oic acid, isopropyl ester
Supplier: Cayman Chemical
Supplier-Nr: 16818

Properties

Application: Bioactive lipid assays
MW: 432.6 D
Formula: C26H40O5
Purity: >98%
Format: Solution

Database Information

CAS : 145773-22-4| Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225, H303, H319, H336, H361
P Phrases: P201, P202, P210, P233, P240, P241, P242, P243, P261, P264, P271, P280, P303+361+353, P304+340, P305+351+338, P308+313, P312, P337+313, P370+378, P403+233, P403+235, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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