15(R)-15-methyl Prostaglandin F2alpha

15(R)-15-methyl Prostaglandin F2alpha
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay16730-500 500 µg -

6 - 10 business days*

74.00€
Cay16730-1 1 mg -

6 - 10 business days*

140.00€
 
15(R)-15-methyl PGF2alpha is a metabolically stable analog of PGF2alpha. 15(R)-15-methyl... more
Product information "15(R)-15-methyl Prostaglandin F2alpha"
15(R)-15-methyl PGF2alpha is a metabolically stable analog of PGF2alpha. 15(R)-15-methyl PGF2alpha is an inactive, prodrug PGF agonist designed for activation by gastric acid after oral administration. Acid-catalyzed epimerization of 15(R)-15-methyl PGF2alpha converts it into the active 15(S)-isomer. The 15(S)-isomer induces luteolysis when injected in rhesus monkeys at a dose of about 12 mg/animal, while the 15(R)-isomer does not. Formal Name: 9alpha,11alpha,15R-trihydroxy-15-methyl-prosta-5Z,13E-dien-1-oic acid. CAS Number: 35864-81-4. Synonyms: 15(R)-15-methyl PGF2alpha. Molecular Formula: C21H36O5. Formula Weight: 368.5. Purity: >95%. Formulation: A solution in methyl acetate. Solubility: 10 mM Na2CO3: >6.5 mg/ml (from PGF2a), DMF: >100 mg/ml (from PGF2a), DMSO: >100 mg/ml (from PGF2a), Ethanol: >100 mg/ml (from PGF2a), PBS pH 7.2: >10 mg/ml (from PGF2a). SMILES: O[C@@H]1C(C/C=C\CCCC(O)=O)[C@@H](/C=C/[C@](C)(O)CCCCC)[C@H](O)C1. InChi Code: InChI=1S/C21H36O5/c1-3-4-9-13-21(2,26)14-12-17-16(18(22)15-19(17)23)10-7-5-6-8-11-20(24)25/h5,7,12,14,16-19,22-23,26H,3-4,6,8-11,13,15H2,1-2H3,(H,24,25)/b7-5-,14-12+/t16?,17-,18+,19-,21-/m1/s1. InChi Key: DLJKPYFALUEJCK-YLFQPMNTSA-N.
Keywords: 15(R)-15-methyl PGF2alpha, 9alpha,11alpha,15R-trihydroxy-15-methyl-prosta-5Z,13E-dien-1-oic acid
Supplier: Cayman Chemical
Supplier-Nr: 16730

Properties

Application: Bioactive lipid assays
MW: 368.5 D
Formula: C21H36O5
Purity: >95%
Format: Solution

Database Information

CAS : 35864-81-4| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: EUH066, H225, H319, H336, H360
P Phrases: , P201, P202, P210, P233, P240, P241, P242, P243, P261, P264, P271, P280, P303+361+353, P304+340, P305+351+338, P308+313, P312, P337+313, P370+378, P403+233, P403+235, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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