(±)14(15)-EpETE

(±)14(15)-EpETE
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10173-25 25 µg -

5 - 10 business days*

48.00€
Cay10173-50 50 µg -

5 - 10 business days*

90.00€
Cay10173-100 100 µg -

5 - 10 business days*

172.00€
Cay10173-500 500 µg -

5 - 10 business days*

760.00€
 
EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from... more
Product information "(±)14(15)-EpETE"
EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-derived (prostacyclin) vasodilators. Cytochrome P450 (CYP450) metabolism of polyunsaturated fatty acids, produces epoxides such as (±)14(15)-EpETrE (Cay-50651) which are prime candidates for the actual active mediator. However, the CYP450 metabolites of eicosapentaenoic acid (EPA, Cay-90110) and docosahexaenoic acid (DHA, Cay-90310) have been little studied relative to arachidonate epoxygenase metabolites. (±)14(15)-EpETE is the omega-3 homolog of 14(15)-EpETrE, derived via epoxidation of the 14,15-double bond of EPA. The EDHF activity of (±)14(15)-EpETE has not yet been determined. Formal Name: (±)14,15-epoxy-5Z,8Z,11Z,17Z-eicosatetraenoic acid. CAS Number: 131339-24-7. Synonyms: (±)14,15 EEQ, (±)14,15-epoxy Eicosatetraenoic Acid. Molecular Formula: C20H30O3. Formula Weight: 318.5. Purity: >90%. Formulation: A solution in ethanol. Solubility: DMF: 50 mg/ml, DMSO: 50 mg/ml, Ethanol: 50 mg/ml, PBS (pH 7.2): 1 mg/ml. SMILES: CC/C=C\C[C@@H]1[C@@H](O1)C/C=C\C/C=C\C/C=C\CCCC(O)=O. InChi Code: InChI=1S/C20H30O3/c1-2-3-12-15-18-19(23-18)16-13-10-8-6-4-5-7-9-11-14-17-20(21)22/h3-4,6-7,9-10,12-13,18-19H,2,5,8,11,14-17H2,1H3,(H,21,22)/b6-4-,9-7-,12-3-,13-10-/t18-,19+/m1/s1. InChi Key: RGZIXZYRGZWDMI-IXQKDQKQSA-N.
Keywords: (±)14,15 EEQ, (±)14,15-epoxy Eicosatetraenoic Acid, (±)14,15-epoxy-5Z,8Z,11Z,17Z-eicosatetraenoic acid
Supplier: Cayman Chemical
Supplier-Nr: 10173

Properties

Application: Bioactive lipid assays
MW: 318.5 D
Formula: C20H30O3
Purity: >90%
Format: Solution

Database Information

CAS : 131339-24-7| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225
P Phrases: P210, P233, P240, P241, P242, P243, P280, P303+361+353, P370+378, P403+235, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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