14(15)-EET Ethanolamide

14(15)-EET Ethanolamide
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10008599-25 25 µg -

6 - 10 business days*

Cay10008599-50 50 µg -

6 - 10 business days*

Cay10008599-100 100 µg -

6 - 10 business days*

Arachidonyl ethanolamide (AEA) is an endogenous lipid neurotransmitter with cannabinergic... more
Product information "14(15)-EET Ethanolamide"
Arachidonyl ethanolamide (AEA) is an endogenous lipid neurotransmitter with cannabinergic activity, binding to both the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. Fatty acid amide hydrolase (FAAH) is the enzyme responsible for the hydrolysis and inactivation of AEA. Metabolism of AEA by cyclooxygenase-2, leading to formation of prostaglandin ethanolamides, and by lipoxygenases has also been documented. (±)14(15)-EET ethanolamide is a potential cytochrome P450 (CYP450) metabolite of arachidonoyl ethanolamide (AEA), although specific stereochemistry rather than a racemic mixture would likely ensue from enzymatic metabolism. CYP450 metabolism of AEA may be particularly relevant under conditions of fatty acid amide hydrolase inhibition. Evidence for the formation of (±)14(15)-EET ethanolamide in vivo has not been documented. Formal Name: N-(2-hydroxyethyl)-(±)14(15)-epoxy-5Z,8Z,11Z-eicosatrienamide. Synonyms: (±)14,15-EpETrE Ethanolamide, (±)14(15)-Epoxy Eicosatrienoyl Ethanolamide. Molecular Formula: C22H37NO3. Formula Weight: 363.5. Purity: >95%. Formulation: A solution in ethanol. Solubility: DMF: 30 mg/ml, DMSO: 20 mg/ml, Ethanol: 30 mg/ml, Ethanol:PBS (pH 7.2) (1:6): 0.5 mg/ml. SMILES: CCCCC[C@H]1O[C@H]1C/C=C\C/C=C\C/C=C\CCCC(=O)NCCO. InChi Code: InChI=1S/C22H37NO3/c1-2-3-12-15-20-21(26-20)16-13-10-8-6-4-5-7-9-11-14-17-22(25)23-18-19-24/h4,6-7,9-10,13,20-21,24H,2-3,5,8,11-12,14-19H2,1H3,(H,23,25)/b6-4-,9-7-,13-10-/t20-,21+/m1/s1. InChi Key: WYVHLKMCZZDTOU-XYFYYYGJSA-N.
Keywords: (±)14(15)-Epoxy Eicosatrienoyl Ethanolamide, (±)14,15-EpETrE Ethanolamide, N-(2-hydroxyethyl)-(±)14(15)-epoxy-5Z,8Z,11Z-eicosatrienamide
Supplier: Cayman Chemical
Supplier-Nr: 10008599


Application: Bioactive lipid assays
MW: 363.5 D
Formula: C22H37NO3
Purity: >95%
Format: Solution

Database Information

Handling & Safety

Storage: -80°C
Shipping: -20°C (International: -80°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225
P Phrases: P210, P233, P240, P241, P242, P243, P280, P303+361+353, P370+378, P403+235, P501
Our products are for laboratory research use only: Not for administration to humans!
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