13-OxoODE-d3

13-OxoODE-d3 contains three deuterium atoms at the 9, 10, and 12 positions. It is intended for use as an internal standard for the quantification of 13-OxoODE by GC- or LC-mass spectrometry. 13-oxoODE is produced from 13-HODE by a NAD+-dependent dehydrogenase present in rat colonic mucosa. 13-OxoODE stimulates cell proliferation when instilled intrarectally in rats. 13-OxoODE has also been detected in preparations of rabbit reticulocyte plasma and mitochondrial membranes, mostly esterified to phospholipids. Production of 13-oxoODE is putatively linked to the maturation of reticulocytes to erythrocytes through the activity of 15-LO.Formal Name: 13-oxo-9Z,11E-9,10,12,-d3-octadecadienoic acid. Synonyms: 13-KODE-d3. Molecular Formula: C18H27D3O3. Formula Weight: 297.5. Purity: >99% deuterated forms (d1-d3). Formulation: (Request formulation change), A solution in acetonitrile. Solubility: DMF: 50 mg/ml, DMSO: 50 mg/ml, Ethanol: 50 mg/ml, PBS (pH 7.2): 1 mg/ml. lambdamax: 275 nm. SMILES: CCCCCC(/C([2H])=C/C([2H])=C([2H])\CCCCCCCC(O)=O)=O. InChi Code: InChI=1S/C18H30O3/c1-2-3-11-14-17(19)15-12-9-7-5-4-6-8-10-13-16-18(20)21/h7,9,12,15H,2-6,8,10-11,13-14,16H2,1H3,(H,20,21)/b9-7-,15-12+/i7D,9D,15D. InChi Key: JHXAZBBVQSRKJR-POQBIENVSA-N.