12(S)-HpETE

12(S)-HpETE
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay44570-25 25 µg -

6 - 10 business days*

133.00€
Cay44570-50 50 µg -

6 - 10 business days*

252.00€
Cay44570-100 100 µg -

6 - 10 business days*

478.00€
Cay44570-250 250 µg -

6 - 10 business days*

1,060.00€
 
12(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of... more
Product information "12(S)-HpETE"
12(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of platelet or leukocyte 12-lipoxygenase (12-LO) on arachidonic acid. It activates human blood leukocyte 5-LO, resulting in the synthesis of 5(S)-HETE, leukotriene B4 (LTB4), and 5(S),12(S)-DiHETE. Rat lung metabolizes 12(S)-HpETE to 8,11,12- and 10,11,12-trihydroxyeicostrienoic acids. 12(S)-HpETE is the mediator of many biological functions, including induction of c-fos and c-jun, activation of AP-1, and endothelium-dependent vasoconstriction. It mediates the inhibitory synaptic response to FMRF-amide in Aplysia sensory neurons and inhibits Ca2+/calmodulin-dependent protein kinase II from rat brain cortex. Formal Name: 12S-hydroperoxy-5Z,8Z,10E,14Z-eicosatetraenoic acid. CAS Number: 71774-10-2. Molecular Formula: C20H32O4. Formula Weight: 336.5. Purity: >98%. Formulation: A solution in ethanol. Solubility: 0.1 M Na2CO3: 2 mg/ml, DMF: Miscible, DMSO: Miscible, Ethanol: Miscible, PBS pH 7.2: 0.8 mg/ml. lambdamax: 237 nm. SMILES: CCCCC/C=C\C[C@H](OO)/C=C/C=C\C/C=C\CCCC(O)=O. InChi Code: InChI=1S/C20H32O4/c1-2-3-4-5-10-13-16-19(24-23)17-14-11-8-6-7-9-12-15-18-20(21)22/h7-11,13-14,17,19,23H,2-6,12,15-16,18H2,1H3,(H,21,22)/b9-7-,11-8-,13-10-,17-14+. InChi Key: ZIOZYRSDNLNNNJ-VXBMJZGYSA-N.
Keywords: 12S-hydroperoxy-5Z,8Z,10E,14Z-eicosatetraenoic acid
Supplier: Cayman Chemical
Supplier-Nr: 44570

Properties

Application: Bioactive lipid assays
MW: 336.5 D
Formula: C20H32O4
Purity: >98%
Format: Solution

Database Information

CAS : 71774-10-2| Find alternatives

Handling & Safety

Storage: -80°C
Shipping: -20°C (International: -80°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225
P Phrases: P210, P233, P240, P241, P242, P243, P280, P303+361+353, P370+378, P403+235, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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