12(R)-HETE

12(R)-HETE
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay34560-25 25 µg -

3 - 10 business days*

144.00€
Cay34560-50 50 µg -

3 - 10 business days*

274.00€
Cay34560-100 100 µg -

3 - 10 business days*

403.00€
 
Biosynthesis of 12(R)-HETE in invertebrates is via lipoxygenation of arachidonic acid... more
Product information "12(R)-HETE"
Biosynthesis of 12(R)-HETE in invertebrates is via lipoxygenation of arachidonic acid (Cay-90010). In mammals, 12(R)-HETE can be produced by 12(R)-LOs and also by CYP450 oxidation. The activity of 12(R)-HETE in mammals is predominantly proinflammatory. 12(R)-HETE exhibits dose-dependent leukocyte chemotaxis at concentrations as low as 100 nM, and lowers intraocular pressure in rabbits. Formal Name: 12R-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoic acid. CAS Number: 82337-46-0. Molecular Formula: C20H32O3. Formula Weight: 320.5. Purity: >98%. Formulation: A solution in ethanol. Solubility: 0.1 M Na2CO3: 2 mg/ml, DMF: Miscible, DMSO: Miscible, Ethanol: Miscible, PBS pH 7.2: 0.8 mg/ml. lambdamax: 236 nm. SMILES: CCCCC/C=C\C[C@@H](O)/C=C/C=C\C/C=C\CCCC(O)=O. InChi Code: InChI=1S/C20H32O3/c1-2-3-4-5-10-13-16-19(21)17-14-11-8-6-7-9-12-15-18-20(22)23/h7-11,13-14,17,19,21H,2-6,12,15-16,18H2,1H3,(H,22,23)/b9-7-,11-8-,13-10-,17-14+/t19-/m1/s1. InChi Key: ZNHVWPKMFKADKW-ZYBDYUKJSA-N.
Keywords: 12R-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoic acid
Supplier: Cayman Chemical
Supplier-Nr: 34560

Properties

Application: Bioactive lipid assays
MW: 320.5 D
Formula: C20H32O3
Purity: >98%
Format: Solution

Database Information

CAS : 82337-46-0| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225
P Phrases: P210, P233, P240, P241, P242, P243, P280, P303+361+353, P370+378, P403+235, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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