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11beta-13,14-dihydro-15-keto PGF2alpha is a metabolite of PGD2 (Cay-12010) in the 15-hydroxy PGDH... more
Product information "11beta-13,14-dihydro-15-keto Prostaglandin F2alpha"
11beta-13,14-dihydro-15-keto PGF2alpha is a metabolite of PGD2 (Cay-12010) in the 15-hydroxy PGDH pathway. Infusion or inhalation of tritiated PGD2 in normal males results in the appearance of peak levels of both 11beta-PGF2alpha, as the immediate product, and 11beta-13,14-dihydro-15-keto PGF2alpha in the plasma within 10 minutes. Homogenates of human lung metabolize PGD2 first to 11beta-PGF2alpha and then to 11beta-15-keto-PGF2alpha in the presence of NAD+, but not 11beta-13,14-dihydro-15-keto PGF2alpha. Guinea pig liver and kidney homogenates metabolize PGD2 to 11beta-13,14-dihydro-15-keto PGF2alpha, via 11beta-PGF2alpha, in the presence of NAD+ and NADP+. Formal Name: 9alpha,11beta-dihydroxy-15-oxo-prost-5Z-en-1-oic acid. CAS Number: 107615-77-0. Synonyms: 11beta-13,14-dihydro-15-keto PGF2alpha, 11-epi-13,14-dihydro-15-keto PGF2alpha. Molecular Formula: C20H34O5. Formula Weight: 354.5. Purity: >95%. Formulation: A solution in methyl acetate. Solubility: 10 mM Na2CO3: >6.5 mg/ml (from PGF2a), DMF: >100 mg/ml (from PGF2a), DMSO: >100 mg/ml (from PGF2a), Ethanol: >100 mg/ml (from PGF2a), PBS pH 7.2: >10 mg/ml (from PGF2a). SMILES: O[C@@H]1[C@H](C/C=C\CCCC(O)=O)[C@@H](CCC(CCCCC)=O)[C@@H](O)C1. InChi Code: InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,16-19,22-23H,2-3,5-6,8-14H2,1H3,(H,24,25)/b7-4-/t16-,17-,18+,19+/m1/s1. InChi Key: VKTIONYPMSCHQI-KGILNJEGSA-N.
Keywords: | 11-epi-13,14-dihydro-15-keto PGF2alpha, 11beta-13,14-dihydro-15-keto PGF2alpha, 9alpha,11beta-dihydroxy-15-oxo-prost-5Z-en-1-oic acid |
Supplier: | Cayman Chemical |
Supplier-Nr: | 16540 |
Properties
Application: | Bioactive lipid assays |
MW: | 354.5 D |
Formula: | C20H34O5 |
Purity: | >95% |
Format: | Solution |
Database Information
CAS : | 107615-77-0| Find alternatives |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Signal Word: | Danger |
GHS Hazard Pictograms: | ![]() ![]() |
H Phrases: | EUH066, H225, H319, H336 |
P Phrases: | , P210, P233, P240, P241, P242, P243, P261, P264, P271, P280, P303+361+353, P304+340, P305+351+338, P312, P337+313, P370+378, P403+233, P403+235, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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