10-Nitrooleate

10-Nitrooleate
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10008043-50 50 µg -

6 - 10 business days*

32.00€
Cay10008043-100 100 µg -

6 - 10 business days*

50.00€
Cay10008043-500 500 µg -

6 - 10 business days*

210.00€
Cay10008043-1 1 mg -

6 - 10 business days*

369.00€
 
Nitrated unsaturated fatty acids, such as 10- and 12-nitrolinoleate (LNO2, Cay-10037),... more
Product information "10-Nitrooleate"
Nitrated unsaturated fatty acids, such as 10- and 12-nitrolinoleate (LNO2, Cay-10037), cholesteryl nitrolinoleate, and nitrohydroxylinoleate, represent a new class of endogenous lipid-derived signalling molecules. LNO2 isomers serve as potent endogenous ligands for PPARgamma and can also decompose or be metabolized to release nitric oxide. 10-Nitrooleate is one of two regioisomers of nitrooleate, the other being 9-nitrooleate (Cay-10008042) (OA-NO2, used for the mixture of isomers), which are formed by nitration of oleic acid in approximately equal proportions in vivo. Peroxynitrite, acidified nitrite, and myeloperoxidase in the presence of H2O2 and nitrite, all mediate the nitration of oleic acid. OA-NO2 is found in human plasma as the free acid and esterified in phospholipids at concentrations of 619 ± 52 nM and 302 ± 369 nM, respectively. OA-NO2 activates PPARgamma approximately 7-fold at a concentration of 1 µM and effectively promotes differentiation 3T3-L1 preadipocytes to adipocytes at 3 µM. Formal Name: 10-nitro-9E-octadecenoic acid. CAS Number: 875685-46-4. Synonyms: 10-Nitrooleic Acid, 10-nitro-9-trans-Octadecenoic Acid. Molecular Formula: C18H33NO4. Formula Weight: 327.5. Purity: >98%. Formulation: A solution in ethanol. Solubility: Ethanol: 1 mg/ml. lambdamax: 255 nm. SMILES: CCCCCCCC/C([N+]([O-])=O)=C\CCCCCCCC(O)=O. InChi Code: InChI=1S/C18H33NO4/c1-2-3-4-5-8-11-14-17(19(22)23)15-12-9-6-7-10-13-16-18(20)21/h15H,2-14,16H2,1H3,(H,20,21)/b17-15+. InChi Key: WRADPCFZZWXOTI-BMRADRMJSA-N.
Keywords: 10-nitro-9-trans-Octadecenoic Acid, 10-Nitrooleic Acid, 10-nitro-9E-octadecenoic acid
Supplier: Cayman Chemical
Supplier-Nr: 10008043

Properties

Application: Bioactive lipid assays
MW: 327.5 D
Formula: C18H33NO4
Purity: >98%
Format: Solution

Database Information

CAS : 875685-46-4| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225
P Phrases: P210, P233, P240, P241, P242, P243, P280, P303+361+353, P370+378, P403+235, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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