1-Stearoyl-rac-glycerol-d40

1-Stearoyl-rac-glycerol-d40 is intended for use as an internal standard for the quantification of 1-stearoyl-rac-glycerol (Cay-26827) by GC- or LC-MS. 1-Stearoyl-rac-glycerol is a monoacylglycerol that contains stearic acid (Cay-10011298) at the sn-1 position. 1-Stearoyl-rac-glycerol levels are decreased in tumor tissue in a mouse model of azoxymethane-induced colorectal carcinogenesis. Levels of 1-stearoyl-rac-glycerol are decreased in lung tissue from patients with adenocarcinoma, but are increased in the serum of patients with Buruli ulcer and in the cerebrospinal fluid of patients with the inflammatory demyelinating diseases multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), and idiopathic transverse myelitis (ITM). 1-Stearoyl-rac-glycerol has been used in the composition of transfersomes for transdermal delivery of doxorubicin (Cay-15007) in rats, leading to doxorubicin accumulation in lymph nodes, spleen, and heart.Formal Name: octadecanoic-2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,12,12,13,13,14,14,15,15,16,16,17,17,18,18,18-d35 acid, 2,3-dihydroxypropyl-1,1,2,3,3-d5 ester. CAS Number: 2692624-09-0. Synonyms: 18:0-d40-MG, 1-Monostearin-d40, MG(18:0-d40/0:0/0:0). Molecular Formula: C21H2D40O4. Formula Weight: 398.8. Purity: >99% deuterated forms (d1-d40). Formulation: (Request formulation change), A crystalline solid. Solubility: Chloroform: 50 mg/ml. SMILES: O=C(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])OC([2H])([2H])C(O)([2H])C([2H])([2H])O. InChi Code: InChI=1S/C21H42O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-19-20(23)18-22/h20,22-23H,2-19H2,1H3/i1D3,2D2,3D2,4D2,5D2,6D2,7D2,8D2,9D2,10D2,11D2,12D2,13D2,14D2,15D2,16D2,17D2,18D2,19D2,20D. InChi Key: VBICKXHEKHSIBG-UHFXHMRYSA-N.