1-Stearoyl-2-Oleoyl-sn-glycero-3-PC

1-Stearoyl-2-oleoyl-sn-glycero-3-PC is a phospholipid containing stearic acid (Cay-10011298) and palmitic acid (Cay-10006627) at the sn-1 and sn-2 positions, respectively. It has been used in the generation of lipid nanoparticles (LNPs) for the delivery of plasmid DNA in vitro. Liposomes containing 1-stearoyl-2-oleoyl-sn-glycero-3-PC and encapsulating the acetylcholinesterase (AChE) reactivator HI-6 (asoxime, Cay-18607) increase the cerebral AChE reactivation rate by 10% compared with HI-6 alone in a mouse model of brain poisoning induced by the organophosphate nerve agent soman. It has also been found in whey protein phospholipid concentrate (WPPC).Formal Name: (7R)-4-hydroxy-N,N,N-trimethyl-10-oxo-7-[[(9Z)-1-oxo-9-octadecen-1-yl]oxy]-3,5,9-trioxa-4-phosphaheptacosan-1-aminium, 4-oxide, inner salt. CAS Number: 56421-10-4. Synonyms: 1-Octadecanoyl-2-(9Z)-Octadecenoyl-sn-glycero-3-Phosphatidylcholine, 1-Octadecanoyl-2-(9Z)-Octadecenoyl-sn-glycero-3-Phosphocholine, 18:0/18:1-PC, PC(18:0/18:1), 1,2-SOPC, L-alpha-1-Stearoyl-2-Oleoylphosphatidylcholine. Molecular Formula: C44H86NO8P. Formula Weight: 788.1. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: Ethanol: 30 mg/ml. SMILES: O=C(CCCCCCCCCCCCCCCCC)OC[C@@H](OC(CCCCCCC/C=C\CCCCCCCC)=O)COP(OCC[N+](C)(C)C)([O-])=O. InChi Code: InChI=1S/C44H86NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h21,23,42H,6-20,22,24-41H2,1-5H3/b23-21-/t42-/m1/s1. InChi Key: ATHVAWFAEPLPPQ-VRDBWYNSSA-N. Side Chain Carbon Sum: 36:1.