1-Linoleoyl Glycerol

1-Linoleoyl Glycerol
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10008869-1 1 mg -

3 - 10 business days*

20.00€
Cay10008869-5 5 mg -

3 - 10 business days*

90.00€
Cay10008869-10 10 mg -

3 - 10 business days*

160.00€
Cay10008869-25 25 mg -

3 - 10 business days*

350.00€
 
Platelet-activating factor (PAF) is a biologically active phospholipid synthesized by a variety... more
Product information "1-Linoleoyl Glycerol"
Platelet-activating factor (PAF) is a biologically active phospholipid synthesized by a variety of stimulated cells that acts as a mediator of platelet aggregation, inflammation, and allergy. PAF is converted to the biologically inactive lyso-PAF by the enzyme PAF acetylhydrolase (PAF-AH). Recently, plasma PAF-AH has been linked to atherosclerosis and may be a positive risk factor for coronary heart disease in humans. 1-Linoleoyl glycerol (1-LG) is a fatty acid glycerol that has been isolated from S. chinensis roots. It inhibits PAF-AH with an IC50 of 45 µM. 1-LG has potential application in cholesterol lowering and antiatherogenic activity. Formal Name: 9Z,12Z-octadecadienoic acid, 1-glyceryl ester. CAS Number: 2277-28-3. Synonyms: 1-LG. Molecular Formula: C21H38O4. Formula Weight: 354.5. Purity: >90%. Formulation: A solution in acetonitrile. Solubility: DMF: 10 mg/ml, Ethanol: 10 mg/ml, Ethanol:PBS (pH 7.2) (1:1): 0.5 mg/ml. SMILES: CCCCC/C=C\C/C=C\CCCCCCCC(OCC(O)CO)=O. InChi Code: InChI=1S/C21H38O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-19-20(23)18-22/h6-7,9-10,20,22-23H,2-5,8,11-19H2,1H3/b7-6-,10-9-. InChi Key: WECGLUPZRHILCT-HZJYTTRNSA-N. Side Chain Carbon Sum: 18:2.
Keywords: 1-LG, 9Z,12Z-octadecadienoic acid, 1-glyceryl ester
Supplier: Cayman Chemical
Supplier-Nr: 10008869

Properties

Application: Bioactive lipid assays
MW: 354.5 D
Formula: C21H38O4
Purity: >90%
Format: Solution

Database Information

CAS : 2277-28-3| Find alternatives

Handling & Safety

Storage: -80°C
Shipping: -20°C (International: -80°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225, H302+312+332, H319
P Phrases: , P210, P233, P240, P241, P242, P243, P264, P280, P303+361+353, P305+351+338, P337+313, P370+378, P403+235, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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