1,2-Dipalmitoyl-3-trimethylammoniumpropane (chloride)

DPTAP is a cationic lipid that has been used as a transfection reagent in vitro and in vivo and in the formation of liposomes and microbubbles. Microbubbles containing DPTAP and encapsulating the microRNA (miRNA) miR-145 reduce atherosclerotic plaque area by 48.04% using ultrasound-targeted microbubble destruction (UTMD) in ApoE-/- mice in a model of atherosclerosis induced by a high-fat diet.Formal Name: N,N,N-trimethyl-2,3-bis[(1-oxohexadecyl)oxy]-1-propanaminium, monochloride. CAS Number: 139984-36-4. Synonyms: DPTAP, 16:0 TAP. Molecular Formula: C38H76NO4 . Cl. Formula Weight: 646.5. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: PBS (pH 7.2): Slightly soluble. SMILES: O=C(OC(C[N+](C)(C)C)COC(CCCCCCCCCCCCCCC)=O)CCCCCCCCCCCCCCC.[Cl-]. InChi Code: InChI=1S/C38H76NO4.ClH/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-37(40)42-35-36(34-39(3,4)5)43-38(41)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2,/h36H,6-35H2,1-5H3,1H/q+1,/p-1. InChi Key: KYARZEFZZOGPGS-UHFFFAOYSA-M.