Octadecyl Rhodamine B chloride

Octadecyl Rhodamine B chloride (R18) is a lipophilic fluorescent dye widely used in membrane biology and cell labeling studies. R18 is used in dequenching assays to monitor liposome fusion or virus-cell membrane fusion. It incorporates into plasma membranes for cell tracking, membrane dynamics, or cell-cell interaction studies. It can be used to label synthetic vesicles to study endocytosis, drug delivery, or membrane trafficking. R18 has also been used as acceptor in FRET studies on liposomes. The fluorescence of octadecyl rhodamine B in membranes is quenched at high dye concentration but is released at dilution. This property makes the dye useful for membrane fusion assays. Spectral Data: lambdaEx/lambdaEm (MeOH) = 556/580nm.