Fluoresceinamine Labeled Sodium Hyaluronate (U1)

Hyaluronan (HA) is a glycosaminoglycan composed of repeating disaccharide units of N-acetyl-D-glucosamine (GlcNAc) and D-glucuronic acid (GlcUA). HA is abundant in synovial fluid, skin, umbilical cord, and vitreous body exists as unbranched polysaccharide chains. This product is prepared by the fluorescent labeling of HA according to the method of Ogamo et al.1). Fluoresceinamine molecules are chemically attached to carboxyl groups of the GlcUA of HA. This solution is dissolved in PBS (-) and sterilized by filtration. The endotoxin content is in accordance with the product specifications. The excitation wavelength is 490-500 nm and the emission wavelength is 515-525 nm.