Fluo-8L(TM), sodium salt

Fluo-8L(TM), sodium salt
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABD-21098 500 µg (10 x 50 µg) -

3 - 8 business days*

ABD-21099 1 mg -

3 - 8 business days*

Calcium measurement is critical for numerous biological investigations. Fluorescent probes that... more
Product information "Fluo-8L(TM), sodium salt"
Calcium measurement is critical for numerous biological investigations. Fluorescent probes that show spectral responses upon binding Ca2 have enabled researchers to investigate changes in intracellular free Ca2 concentrations by using fluorescence microscopy, flow cytometry, fluorescence spectroscopy and fluorescence microplate readers. Fluo-3 and Fluo-4 are most commonly used among the visible light-excitable calcium indicators. However, Fluo-3 AM and Fluo-4 AM are only moderately fluorescent in live cells upon esterase hydrolysis, and require harsh cell loading conditions to maximize their cellular calcium responses. Fluo-8® dyes are developed to improve cell loading and calcium response while maintaining the convenient Fluo-3 and Fluo-4 spectral wavelength of maximum excitation @ about 490 nm and maximum emission @ about 520 nm. Fluo-8® AM only requires room temperature while Fluo-3 AM and Fluo-4 AM require 37 ?C cell loading. In addition, Fluo-8® is 2 times brighter than Fluo-4 AM, and 4 times brighter than Fluo-3 AM. AAT Bioquest offers a set of our outstanding Fluo-8® reagents with different calcium binding affinities (Fluo-8®: Kd = 389 nM, Fluo-8H: Kd = 232 nM, Fluo-8L: Kd = 1.86 µM, Fluo-8FF: Kd = 10 µM). We also offer versatile packing sizes to meet your special needs, e.g., 1 mg, 10x50 µg, 20x50 µg, HTS packages with no additional packaging charge. ***Patents Pending***
Supplier: AAT Bioquest
Supplier-Nr: 21098


Application: Calcium Indicator

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Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Signal Word: Warning
Our products are for laboratory research use only: Not for administration to humans!
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