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Coelenterazine is a luciferin, a light-emitting biomolecule that serves as a substrate for... more
Product information "Coelenterazine"
Coelenterazine is a luciferin, a light-emitting biomolecule that serves as a substrate for luciferases or as a constituent of photoproteins, including aequorin. The oxidation of coelenterazine to coelenteramide is accompanied by emission of blue light (emission maximum, 460-470 nm). Luciferase-mediated oxidation of coelenterazine or a derivative is used as an energy donor, typically to a form of green or yellow fluorescent protein, in bioluminescent resonance energy transfer studies. Alternatively, the calcium-mediated release of coelenterazine from aequorin, followed by non-enzymatic oxidation of this compound, results in bioluminescence. As light emission depends on both calcium and cellular redox status, this reaction is used to non-fluorescently detect changes in calcium level and redox status.Formal Name: 6-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]-8-(phenylmethyl)-imidazo[1,2-a]pyrazin-3(7H)-one. CAS Number: 55779-48-1. Synonyms: Luciferin (Oplophorus), Preluciferin (Watasenia). Molecular Formula: C26H21N3O3. Formula Weight: 423.5. Purity: >85%. Emission: 460-470 nm. Formulation: (Request formulation change), A crystalline solid. Solubility: Ethanol: 0.5 mg/ml, Methanol: 0.5 mg/ml. SMILES: OC1=CC=C(C2=CN3C(N=C(CC4=CC=C(O)C=C4)C3=O)=C(CC5=CC=CC=C5)N2)C=C1. InChi Code: InChI=1S/C26H21N3O3/c30-20-10-6-18(7-11-20)15-23-26(32)29-16-24(19-8-12-21(31)13-9-19)27-22(25(29)28-23)14-17-4-2-1-3-5-17/h1-13,16,27,30-31H,14-15H2. InChi Key: YHIPILPTUVMWQT-UHFFFAOYSA-N.
Keywords: | Luciferin (Oplophorus), Preluciferin (Watasenia), 6-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]-8-(phenylmethyl)-imidazo[1,2-a]pyrazin-3(7H)-one |
Supplier: | Cayman Chemical |
Supplier-Nr: | 16123 |
Properties
Application: | Luciferase substrate |
MW: | 423.5 D |
Formula: | C26H21N3O3 |
Purity: | >85% |
Format: | Crystalline Solid |
Database Information
CAS : | 55779-48-1| Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: -20°C) |
Signal Word: | Warning |
GHS Hazard Pictograms: |
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H Phrases: | H315, H319, H335, H413 |
P Phrases: | P261, P264, P271, P273, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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