Dyes and Labeling Reagents

This category comprises chemicals for permanent and temporary labeling of organelles, proteins, and other molecules. For example, this includes the covalent linkage of a target protein, such as an antibody, with a fluorescent dye/fluorophore, allowing detection of the target protein in microscopic experiments. For the purpose of detection, proteins can also be coupled with reporter enzymes (e.g. HRP) or radioactive isotopes. To facilitate the purification of a target protein, biotinylation followed by streptavidine affinity binding has proven to be effective.

This category comprises chemicals for permanent and temporary labeling of organelles, proteins, and other molecules. For example, this includes the covalent linkage of a target protein, such as an... read more »
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Dyes and Labeling Reagents

This category comprises chemicals for permanent and temporary labeling of organelles, proteins, and other molecules. For example, this includes the covalent linkage of a target protein, such as an antibody, with a fluorescent dye/fluorophore, allowing detection of the target protein in microscopic experiments. For the purpose of detection, proteins can also be coupled with reporter enzymes (e.g. HRP) or radioactive isotopes. To facilitate the purification of a target protein, biotinylation followed by streptavidine affinity binding has proven to be effective.

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AATOM(TM) 647N TCO
AATOM(TM) 647N TCO

Item number: ABD-2838

Product key features: Ex/Em: 645/663 nm Extinction coefficient: 150,000 cm^(-1)M^(-1) Reactive group: TCO Click Chemistry Conjugation: Provides rapid and copper-free labeling of tetrazine-modified biomolecules with high yield High Quantum Yield & Stability: Provides bright fluorescence with high photostability,...
Application: Rhodamine-based fluorescent dye, red spectral region, similar spectral characteristics as Cy5
291.00€ *
Review
C-Laurdan
C-Laurdan

Item number: Cay43531-1

C-Laurdan is a polarity-sensitive fluorescent probe for lipid rafts and a derivative of the fluorescent membrane probe laurdan (Cay-19706). It displays a two-photon excitation maximum of 820 nm and one-photon absorption/emission maxima of 384/522 nm, respectively, in water. C-Laurdan fluorescence exhibits...
Keywords: N-methyl-N-[6-(1-oxododecyl)-2-naphthalenyl]-glycine
Application: Polarity-sensitive fluorescent probe, lipid rafts studies
CAS 959839-06-6
MW: 397.56 D
From 179.00€ *
Review
Oregon Green(TM) 488 succinimidyl ester
Oregon Green(TM) 488 succinimidyl ester

Item number: Cay43466-10

Oregon GreenTM 488 succinimidyl ester is an amine-reactive fluorescent probe. It has been used in the synthesis of fluorescent DNA probes and to fluorescently label proteins. A related derivative, Oregon GreenTM 488 (Cay-35372), displays absorbance/emission maxima of 490/514 nm, respectively. Formal Name:...
Keywords: 2',7'-Difluorofluorescein succinimidyl ester, OG 488 SE, OG 488 succinimidyl ester,...
Application: Amine-reactive fluorescent probe
CAS 198139-51-4
MW: 509.37 D
From 174.00€ *
Review
CFSE (5-(and 6)-Carboxyfluorescein diacetate, succinimidyl ester) *Mixed isomers*
CFSE (5-(and 6)-Carboxyfluorescein diacetate,...

Item number: ABD-22022

CFDA, SE is an amine reactive FDA derivative that can be used to prepare a variety of FDA conjugates.
Keywords: CFDA-SE
Application: Cell proliferation assays
CAS 150347-59-4
145.00€ *
Review
TMRE (Tetramethylrhodamine ethyl ester)
TMRE (Tetramethylrhodamine ethyl ester)

Item number: ABD-22220

Like JC-1, TMRM and TMRE are widely used for measuring mitochondrial membrane potential besides their selective mitochondrial staining. TMRE is slightly more hydrophobic than TMRM.
Application: Mitochondrial membrane potential assays
CAS 115532-52-0
143.00€ *
Review
FMOC-Lys(5/6-TAMRA)-OH
FMOC-Lys(5/6-TAMRA)-OH

Item number: ABD-5044

A building block for in-sequence Lys labeling by TAMRA.
Application: Building block
291.00€ *
Review
Hexidium Iodide
Hexidium Iodide

Item number: ABD-17562

The nucleic acid stain, hexidium iodide is permeant to mammalian cells and selectively stains almost all gram-positive bacteria in the presence of gram-negative bacteria. Hexidium iodide exhibits excitation/emission maxima of ~518/600 nm upon binding DNA. Generally, both the cytoplasm and nuclei of eukaryotic cells...
Application: Fluorescent nucleic acid stain
CAS 211566-66-4
218.00€ *
Review
Quest Fluo-8H(TM), AM
Quest Fluo-8H(TM), AM

Item number: ABD-21091

Fluorescent probe that show spectral responses upon binding Ca2+. Superior compared to Fluo-3 AM and Fluo-4 AM. (Quest Fluo-8: Kd = 389 nM, Quest Fluo-8H: Kd = 232 nM, Quest Fluo-8L: Kd = 1.86 µM).
Application: Calcium indicator
From 291.00€ *
Review
5(6)-TAMRA, SE (5-(and-6)-Carboxytetramethylrhodamine, succinimidyl ester) *Mixed isomers*
5(6)-TAMRA, SE (5-(and-6)-Carboxytetramethylrhodamine,...

Item number: ABD-370

The succinimidyl esters of 5-TAMRA, 6-TAMRA or the mixed isomers are the primary labeling reagents especially for fluorescent antibodies and avidin derivatives used in immunochemistry.
Application: Labeling
CAS 246256-50-8
From 145.00€ *
Review
iFluor(R) 647-dextran conjugate (average MW = ~10K)
iFluor(R) 647-dextran conjugate (average MW = ~10K)

Item number: ABD-21718

iFluor(R) 647-dextran conjugate (average molecular weight ~10,000 Da) is a hydrophilic fluorescent probe composed of a 10 kDa dextran polymer covalently labeled with iFluor(R) 647, a far-red-emitting dye with excitation and emission maxima at approximately 656 nm and 670 nm, respectively. The relatively low...
Application: Far-red fluorescent dextran, intracellular compartment labeling, vascular permeability monitoring
245.00€ *
Review
Quest Fluo-8H(TM), sodium salt
Quest Fluo-8H(TM), sodium salt

Item number: ABD-21095

Fluorescent probe that show spectral responses upon binding Ca2+. Superior compared to Fluo-3 AM and Fluo-4 AM. (Quest Fluo-8: Kd = 389 nM, Quest Fluo-8H: Kd = 232 nM, Quest Fluo-8L: Kd = 1.86 µM).
Application: Calcium indicator
291.00€ *
Review
Fura-FF, AM [Fura-2FF, AM]
Fura-FF, AM [Fura-2FF, AM]

Item number: ABD-21027

10x50 µg. Ex: 363 nm. Em: 512 nm. Soluble in: Water. Among the ratiometric calcium indicators, Fura-2 and Indo-1 are most commonly used. Fura-2 is excitation-ratioable while Indo-1 is emission-ratioable. Fura-2 is preferred for ratio-imaging microscopy, in which it is more practical to change excitation wavelengths...
Application: Cell-permeant fluorescent calcium indicator acetoxy-methyl ester, HTS assays, Calcium GPCR assays
CAS 348079-12-9
MW: 1023,80 D
291.00€ *
Review
11 from 269 pages