5-JOE NHS ester

JOE is a fluorescein-based xanthene dye that incorporates methoxy groups and chlorine atoms. Its absorption and emission spectra fall between the FAM and TAMRA/ROX channels, making it an ideal fluorophore for multiplex detection applications, such as DNA sequencing. This derivative is an activated N-hydroxysuccinimide (NHS) ester, which is used to label proteins, peptides, amino-modified oligonucleotides, and other target molecules by forming stable amide bonds with amine groups. This versatility makes JOE NHS ester a valuable tool in fluorescence-based research and molecular labeling. Chemical Properties Storage Upon receipt, store at -20°C in the dark. Protect from light and moisture. When stored as indicated, 5-JOE NHS ester is stable for at least 1 year. This product is for Research Use Only· Not for Human or Veterinary or Therapeutic Use CAS number 113394-24-4 Formula C27H17Cl2NO11 Molecular Weight 602.33 HPLC Purity >95% lambdaabs (nm) 533 epsilonmax (M-1 cm-1) 7.5x10^4 lambdafl (nm) 554 CF260 =epsilon260/epsilonmax 0.36 CF280 =epsilon280/epsilonmax 0.28