Ursodeoxycholic Acid (sodium salt)

Ursodeoxycholic Acid (sodium salt)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay15121-250 250 mg -

6 - 10 business days*

109.00€
Cay15121-500 500 mg -

6 - 10 business days*

173.00€
Cay15121-1 1 g -

6 - 10 business days*

299.00€
Cay15121-5 5 g -

6 - 10 business days*

1,057.00€
 
Ursodeoxycholic acid (UDCA) is a secondary bile acid formed via epimerization of chenodeoxycholic... more
Product information "Ursodeoxycholic Acid (sodium salt)"
Ursodeoxycholic acid (UDCA) is a secondary bile acid formed via epimerization of chenodeoxycholic acid (CDCA, Cay-10011286). UDCA is also a metabolite of lithocholic acid (LCA, Cay-20253) in human liver microsomes. It inhibits taurocholic acid (Cay-16215) uptake in HeLa cells expressing recombinant sodium/taurocholate cotransporting polypeptide (NTCP) with an IC50 value of 3.6 µM. UDCA (50 µM) inhibits apoptosis induced by deoxycholic acid (DCA, Cay-20756, Cay-18231) or ethanol in primary rat hepatocytes. Dietary administration of UDCA blocks DCA-induced increases in the number of TUNEL-positive hepatocytes in rats. Formulations containing UDCA have been used in the treatment of primary biliary cirrhosis.Formal Name: 3alpha,7beta-dihydroxy-5beta-cholan-24-oic acid, sodium salt. CAS Number: 31687-65-7. Synonyms: UDCA, Ursodiol. Molecular Formula: C24H39O4 . xNa. Formula Weight: 414.6. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 5 mg/ml, DMSO: 10 mg/ml, Ethanol: 15 mg/ml. SMILES: [O-]C(CC[C@@H](C)[C@@]1([H])CC[C@@]2([H])[C@]3([H])[C@@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C)=O.[Na]. InChi Code: InChI=1S/C24H40O4.Na/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26,/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28),/p-1/t14-,15+,16-,17-,18+,19+,20+,22+,23+,24-,/m1./s1. InChi Key: DOVZGADDWOFQEZ-FUXQPCDDSA-M.
Keywords: UDCA, Ursodiol, (3alpha,5beta,7beta)-3,7-dihydroxy-cholan-24-oic acid, monosodium salt
Supplier: Cayman Chemical
Supplier-Nr: 15121

Properties

Application: Hydrophilic bile acid
MW: 414.6 D
Formula: C24H39O4 . xNa
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 31687-65-7| Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H315, H319, H335
P Phrases: P261, P264, P271, P280, P312, P321, P302+P352, P304+P340, P305+P351+P338, P332+P313, P337+P313, P362+P364, P405, P403+P233, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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