FTAC6

FTAC6 is a detergent that can be used to stabilize membrane proteins. It has a critical micelle concentration (CMC) of 0.37 mM. It has been used in the cell-free synthesis and purification of histidine-tagged MscL, a mechanosensitive membrane channel, as well as in the insertion of MscL into liposomes. FTAC6 has also been used in the synthesis of MscL in vitro and preserves its activity.Formal Name: N1,N3,N5,N7,N9,N11-hexakis(1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl)-12-((3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)thio)dodecane-1,3,5,7,9,11-hexacarboxamide. Formulation: (Request formulation change), A powder. SMILES: [H]C(C(NC(CO)(CO)CO)=O)CC(C(NC(CO)(CO)CO)=O)CC(C(NC(CO)(CO)CO)=O)CC(C(NC(CO)(CO)CO)=O)CC(C(NC(CO)(CO)CO)=O)CC(C(NC(CO)(CO)CO)=O)CSCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F. InChi Code: InChI=1S/C50H83F13N6O24S/c51-45(52,46(53,54)47(55,56)48(57,58)49(59,60)50(61,62)63)3-4-94-9-32(38(93)69-44(25-85,26-86)27-87)8-31(37(92)68-43(22-82,23-83)24-84)7-30(36(91)67-42(19-79,20-80)21-81)6-29(35(90)66-41(16-76,17-77)18-78)5-28(34(89)65-40(13-73,14-74)15-75)1-2-33(88)64-39(10-70,11-71)12-72/h28-32,70-87H,1-27H2,(H,64,88)(H,65,89)(H,66,90)(H,67,91)(H,68,92)(H,69,93). InChi Key: HWROCDJKKCTGBC-UHFFFAOYSA-N.