Detergents

Detergents are amphiphilic, organic chemicals. These substances, also called surfactants (surface active agents), possess a lipophilic tail and a hydrophilic head group. Detergents like Triton X-100 form stable interphases between hydrophobic and hydrophilic compounds. This results in the solubilization of the hydrophobic molecules in water. In research, detergents are used for cell lysis, isolation of poorly soluble proteins (e.g. transmembrane receptors) and for membrane permeabilization. Here, you will find a wide array of non-ionic, cationic, anionic and zwitterionic detergents.

Detergents are amphiphilic, organic chemicals. These substances, also called surfactants ( surf ace act ive a ge nts ), possess a lipophilic tail and a hydrophilic head group. Detergents like... read more »
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Detergents

Detergents are amphiphilic, organic chemicals. These substances, also called surfactants (surface active agents), possess a lipophilic tail and a hydrophilic head group. Detergents like Triton X-100 form stable interphases between hydrophobic and hydrophilic compounds. This results in the solubilization of the hydrophobic molecules in water. In research, detergents are used for cell lysis, isolation of poorly soluble proteins (e.g. transmembrane receptors) and for membrane permeabilization. Here, you will find a wide array of non-ionic, cationic, anionic and zwitterionic detergents.

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CHAPS ((3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate))
CHAPS...

Item number: C3490.5

Non-denaturing zwitterionic detergent with cholic acid and sulfobetaine moieties, used to dissolve biological membranes, useful for protein extraction methods due to its ease of removal by dialysis or gel filtration. Low background UV absorption for protein detection. Designed by Good, et al., and typically referred...
CAS 75621-03-3
MW: 614.90 D
From 88.00€ *
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MEGA-8 (ultrapure)
MEGA-8 (ultrapure)

Item number: AG-CC1-0007-G005

White crystalline powder. Soluble in water (>2g/10ml at 20 °C). Non-ionic water-soluble detergent with nondenaturing properties, Transparent in the UV region, Relatively high critical micelle concentration (CMC) value (79mM/l), Ideal for studying the conformation and function of proteins, keeping the secondary and...
Keywords: N-Octanoyl-N-methylglucamine, OMEGA
Application: Non-ionic water-soluble, nondenaturing detergent, Membrane protein solubilization
CAS 85316-98-9
MW: 321,4 D
From 121.00€ *
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LDAO
LDAO

Item number: Cay25699-1

LDAO is a zwitterionic detergent that can be used to solubilize membrane proteins. It has a critical micelle concentration (CMC) of 1-2 mM. LDAO has been used to solubilize and extract colicin A from the plasma membrane and for inactivation of enveloped viruses. It has also been used in combination with...
Keywords: Dimethyldodecylamine N-oxide, Lauramine Oxide, Lauryldimethylamine Oxide, N-Lauryldimethylamine N-oxide,...
Application: Zwitterionic detergent
CAS 1643-20-5
MW: 229.4 D
From 57.00€ *
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n-Decyl-beta-D-maltoside
n-Decyl-beta-D-maltoside

Item number: Cay25704-1

n-Decyl-beta-D-maltoside is a nonionic surfactant that is commonly used to solubilize and stabilize membrane proteins. It has a critical micelle concentration (CMC) value of 1.8 mM and has been used in the expression of functional recombinant GPCRs.Formal Name: decyl...
Keywords: Decylmaltoside, Decyl-beta-maltopyranoside, Decyl-beta-maltoside, n-Decyl-beta-D-maltopyranoside, decyl...
Application: Nonionic surfactant
CAS 82494-09-5
MW: 482.6 D
From 179.00€ *
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n-Octyl-beta-D-glucopyranoside (ultrapure)
n-Octyl-beta-D-glucopyranoside (ultrapure)

Item number: AG-CC1-0008-G025

Non-ionic detergent for the functional solubilization, isolation, purification and crystallograpy of membrane proteins. Mild, non-denaturing detergent that is used for the solubilization and reconstitution of membrane-bound proteins in their native state and for the preparation of lipid vesicles. Its well-defined...
Keywords: OG, n-Octylglucoside, n-Octyl-beta-D-glucoside, BTB11967
Application: Membrane protein solubilization/isolation/purification/crystallography
CAS 29836-26-8
MW: 292.4 D
From 50.00€ *
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Cholesteryl hemisuccinate
Cholesteryl hemisuccinate

Item number: CDX-C0828-G005

Cholesteryl hemisuccinate (CHEMS) is a cholesterol ester. It is formed by esterifying cholesterol with succinic acid. The chemical structure comprises a cholesterol molecule attached to a succinic acid moiety. It possesses both hydrophilic (water-attracting) and hydrophobic (water-repelling) properties, making it...
Keywords: 3beta-Hydroxy-5-cholestene 3-hemisuccinate, 5-Cholesten-3beta-ol 3-hemisuccinate, Cholesteryl hydrogen succinate
Application: Cholesterol ester, surfactant
CAS 1510-21-0
MW: 486,73 D
From 232.00€ *
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CHAPSO ((3-[(3-Cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulfonate))
CHAPSO...

Item number: C3500.25

Non-denaturing zwitterionic detergent with cholic acid and sulfobetaine moieties, used to dissolve biological membranes, useful for protein extraction methods due to its ease of removal by dialysis or gel filtration. Low background UV absorption for protein detection. Designed by Good, et al., and typically referred...
CAS 82473-24-3
MW: 630.90 D
From 712.00€ *
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n-Octyl-beta-D-thioglucopyranoside
n-Octyl-beta-D-thioglucopyranoside

Item number: Cay17184-1

n-Octyl-beta-D-thioglucopyranoside (OTG) is a low molecular weight nonionic detergent that is commonly used for cell lysis and non-denaturing protein solubilization. It has a critical micelle concentration of 7.9-9.0 mM. OTG is stable in aqueous solutions, resistant to degradation by beta-glucosidases, and easily...
Keywords: Octylthioglucoside, OTG, octyl 1-thio-beta-D-glucopyranoside
Application: Cell lysis, non-denaturing protein solubilization
CAS 85618-21-9
MW: 308.4 D
From 51.00€ *
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n-Octyl-beta-D-thioglucopyranoside (ultrapure)
n-Octyl-beta-D-thioglucopyranoside (ultrapure)

Item number: AG-CC1-0005-G001

Soluble in water or methanol. ? 99% (HPLC) [alpha-Isomer <0.01% (HPLC)] [n-Octanthiol <0.001% (HPLC)] Non-ionic detergent. For functional solubilization, purification and crystallography of membrane proteins. The thioether linkage makes it resistant to degradation by beta-glucosidase enzymes. For the stabilization...
Keywords: OTG, Octylthioglucoside, n-Octyl 1-thio-beta-D-glucopyranoside
Application: Non-ionic detergent, Crystallography
CAS 85618-21-9
MW: 308,4 D
From 61.00€ *
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FLAC6
FLAC6

Item number: Cay24781-100

FLAC6 is a detergent that can be used to solubilize membrane proteins. It has a critical micelle concentration (CMC) of 0.56 mM.Formal Name:...
Keywords: (2R,3R,4R,5R)-2,3,5,6-tetrahydroxy-N-(4,4,5,5,6,6,7,7,8,8,9,9,9-tridecafluorononyl)-4-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-...
Application: Membrane protein solubilization
CAS 2820046-26-0
MW: 717.4 D
From 345.00€ *
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FTAC8
FTAC8

Item number: Cay24787-250

FTAC8 is a detergent that can be used to stabilize membrane proteins. It has a critical micelle concentration (CMC) of 0.02 mM. It has been used in the cell-free synthesis and purification of histidine-tagged MscL, a mechanosensitive membrane channel, as well as in the insertion of MscL into liposomes. FTAC8 has...
Keywords: C8F-TAC,...
Application: Membrane protein stabilization
371.00€ *
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FTAC6
FTAC6

Item number: Cay24786-250

FTAC6 is a detergent that can be used to stabilize membrane proteins. It has a critical micelle concentration (CMC) of 0.37 mM. It has been used in the cell-free synthesis and purification of histidine-tagged MscL, a mechanosensitive membrane channel, as well as in the insertion of MscL into liposomes. FTAC6 has...
Keywords: N1,N3,N5,N7,N9,N11-hexakis(1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl)-12-((3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)t...
Application: Membrane protein stabilization
From 404.00€ *
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