Xevinapant

Item number	Size	Delivery time	Price
TGM-T6763-1mg	1 mg	7 - 10 business days*	37.00€
TGM-T6763-2mg	2 mg	7 - 10 business days*	52.00€
TGM-T6763-5mg	5 mg	7 - 10 business days*	84.00€
TGM-T6763-10mg	10 mg	7 - 10 business days*	133.00€
TGM-T6763-1mL	1 ml	7 - 10 business days*	147.00€
TGM-T6763-25mg	25 mg	7 - 10 business days*	292.00€
TGM-T6763-50mg	50 mg	7 - 10 business days*	552.00€
TGM-T6763-100mg	100 mg	7 - 10 business days*	784.00€
TGM-T6763-200mg	200 mg	7 - 10 business days*	1,060.00€
TGM-T6763-500mg	500 mg	7 - 10 business days*	1,389.00€

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Description: Xevinapant (Debio-1143) is a potent Smac mimetic and an antagonist of IAP (inhibitor... more

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Product information "Xevinapant"

Description: Xevinapant (Debio-1143) is a potent Smac mimetic and an antagonist of IAP (inhibitor of apoptosis protein via E3 ubiquitin ligase), binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 66.4 nM, 1.9 nM, and 5.1 nM, 50- to 100-fold higher affinities than the Smac AVPI peptide. Phase 1. Target: IAP. Smiles: CN[C@@H](C)C(=O)N[C@H]1CN(CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1)C(=O)CC(C)C. References: Cai Q, et al. J Med Chem, 2011, 54(8), 2714-2726.

Keywords:	Debio-1143, AT406, ARRY-334543, SM-406
Supplier:	TargetMol
Supplier-Nr:	T6763

Properties

Application:	Targets diablo (DIABLO, SMAC)
MW:	561.71 D
Formula:	C32H43N5O4

Database Information

CAS :	1071992-99-8\| Matching products
KEGG ID :	K10522 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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