VH 032 Linker 3 (hydrate)

VH 032 linker 3 is a derivative of the proteolysis-targeting chimera technology (PROTAC) building block VHL ligand 1 (Cay-21591).Formal Name: (4R)-N-(5-amino-1-oxopentyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-L-prolinamide, dihydrochloride, hydrate. Molecular Formula: C27H39N5O4S . 2HCl [XH2O]. Formula Weight: 602.6. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: 50 mg/ml, Water: 50 mg/ml. lambdamax: 272 nm. SMILES: O=C([C@@H](NC(CCCCN)=O)C(C)(C)C)N1C[C@H](O)C[C@H]1C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O.Cl.Cl.O. InChi Code: InChI=1S/C27H39N5O4S.2ClH.H2O/c1-17-23(37-16-30-17)19-10-8-18(9-11-19)14-29-25(35)21-13-20(33)15-32(21)26(36)24(27(2,3)4)31-22(34)7-5-6-12-28,,,/h8-11,16,20-21,24,33H,5-7,12-15,28H2,1-4H3,(H,29,35)(H,31,34),2*1H,1H2/t20-,21+,24-,,,/m1.../s1. InChi Key: UUIYTMZCHFYYAE-PQFZTLBESA-N.