Venetoclax
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Venetoclax (ABT-199) is a Bcl-2 inhibitor (Ki<0.01 nM) with potent, selective, and... more
Product information "Venetoclax"
Description: Venetoclax (ABT-199) is a Bcl-2 inhibitor (Ki<0.01 nM) with potent, selective, and orally active properties. Venetoclax has a 3-order-of-magnitude lower affinity for Bcl-xL and Bcl-W (Kis=48/245 nM). Venetoclax induces autophagy and apoptosis. Target: Autophagy, BCL. Smiles: O=C(C1=CC=C(N2CCN(CC2)CC3=C(CC(C)(CC3)C)C4=CC=C(Cl)C=C4)C=C1OC5=CC6=C(NC=C6)N=C5)NS(=O)(C7=CC=C(C([N+]([O-])=O)=C7)NCC8CCOCC8)=O. References: Peirs S, et al. ABT-199 mediated inhibition of BCL-2 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia. Blood. 2014 Dec 11,124(25):3738-47.
| Keywords: | GDC-0199, ABT 199, ABT-199, ABT199 |
| Supplier: | TargetMol |
| Supplier-Nr: | T2119 |
Properties
| MW: | 868.44 D |
| Formula: | C45H50ClN7O7S |
Database Information
| CAS : | 1257044-40-8| Matching products |
| Protein Atlas Nr. : | Adhesion & Structure |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
|
| H Phrases: | H361, H372 |
| P Phrases: | P201, P202, P260, P264, P270, P280, P314, P308+P313, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
Viewed