Vemurafenib
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Vemurafenib (RG7204) is a B-RAF inhibitor that inhibits RAFV600E and c-RAF-1... more
Product information "Vemurafenib"
Description: Vemurafenib (RG7204) is a B-RAF inhibitor that inhibits RAFV600E and c-RAF-1 (IC50=31/48 nM) selectively and potently. Vemurafenib exhibits antitumor activity and is used for the treatment of BRAF V600E mutation-positive melanoma. Target: Autophagy, ACK, Src, MAPK, Raf. Smiles: C(=O)(C=1C=2C(NC1)=NC=C(C2)C3=CC=C(Cl)C=C3)C4=C(F)C(NS(CCC)(=O)=O)=CC=C4F. References: Liu C, et al. Silencing TCF4 Sensitizes Melanoma Cells to Vemurafenib Through Inhibiting GLUT3-Mediated Glycolysis. Onco Targets Ther. 2020 May 29,13:4905-4915.
| Keywords: | PLX4032, RG7204, RO5185426 |
| Supplier: | TargetMol |
| Supplier-Nr: | T2382 |
Properties
| MW: | 489.92 D |
| Formula: | C23H18ClF2N3O3S |
Database Information
| CAS : | 918504-65-1| Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H410 |
| P Phrases: | P273, P391, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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