Valilactone

Description: Valilactone is a fatty acid synthase inhibitor, which is produced by a cultured strain of soil actinomycetes. Target: Others. Smiles: CCCCCC[C@H]1[C@H](C[C@H](CCCCC)OC(=O)[C@@H](NC=O)C(C)C)OC1=O. References: Richardson RD, Ma G, Oyola Y, Zancanella M, Knowles LM, Cieplak P, Romo D, Smith JW. Synthesis of novel beta-lactone inhibitors of fatty acid synthase. J Med Chem. 2008 Sep 11,51(17):5285-96. doi: 10.1021/jm800321h. PubMed PMID: 18710210, PubMed Central PMCID: PMC3172131.