Vacuolin-1

Vacuolin-1 is a cell-permeable inhibitor of lysosomal exocytosis that prevents Ca2+-dependent fusion of lysosomes with the plasma membrane and the release of lysosomal content. It does not affect other membrane-bound organelles (including enlargeosomal exocytosis), disturb the organization of the actin or tubulin cytoskeletal network, nor interfere with trafficking along the endocytic or secretory pathways.Formal Name: 3-iodo-benzaldehyde,2-[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone. CAS Number: 351986-85-1. Molecular Formula: C26H24IN7O. Formula Weight: 577.4. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: Chloroform: 30 mg/ml. lambdamax: 225, 242, 314 nm. SMILES: IC1=CC(/C=N/NC2=NC(N(C3=CC=CC=C3)C4=CC=CC=C4)=NC(N5CCOCC5)=N2)=CC=C1. InChi Code: InChI=1S/C26H24IN7O/c27-21-9-7-8-20(18-21)19-28-32-24-29-25(33-14-16-35-17-15-33)31-26(30-24)34(22-10-3-1-4-11-22)23-12-5-2-6-13-23/h1-13,18-19H,14-17H2,(H,29,30,31,32)/b28-19+. InChi Key: JMEJTSRAQUFNOP-TURZUDJPSA-N.