USP28-IN-4

Item number	Size	Delivery time	Price
TGM-T74794-1mg	1 mg	7 - 10 business days*	53.00€
TGM-T74794-5mg	5 mg	7 - 10 business days*	127.00€
TGM-T74794-10mg	10 mg	7 - 10 business days*	200.00€
TGM-T74794-25mg	25 mg	7 - 10 business days*	404.00€
TGM-T74794-50mg	50 mg	7 - 10 business days*	642.00€
TGM-T74794-100mg	100 mg	7 - 10 business days*	1,013.00€

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Description: USP28-IN-4 is a potent USP28 inhibitor with an IC50 value of 0.04 µM against USP28.... more

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Product information "USP28-IN-4"

Description: USP28-IN-4 is a potent USP28 inhibitor with an IC50 value of 0.04 µM against USP28. USP28-IN-4 exhibits anticancer activity and inhibits USP2, USP7, USP8, USP9x, UCHL3 and UCHL5. USP28-IN-4 is cytotoxic to human colorectal and lung squamous carcinoma cells and dose-dependently downregulates c-Myc cellular levels through the ubiquitin-proteasome system. -proteasome system to dose-dependently downregulate cellular levels of c-Myc. Target: DUB. Smiles: O=C(NC1=CC=C(Cl)C(=C1)C=2C=CC3=C(C2)CNC3)C4=CC=C(C=C4Cl)S(=O)(=O)C. References: Zhou D, et al. Structure-based discovery of potent USP28 inhibitors derived from Vismodegib. Eur J Med Chem. 2023 Jun 5,254:115369.

Supplier:	TargetMol
Supplier-Nr:	T74794

Properties

MW:	461.36 D
Formula:	C22H18Cl2N2O3S

Database Information

CAS :

2931509-15-6| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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