URMC-099

Item number	Size	Delivery time	Price
TGM-T6057-5mg	5 mg	7 - 10 business days*	49.00€
TGM-T6057-1mL	1 ml	7 - 10 business days*	51.00€
TGM-T6057-10mg	10 mg	7 - 10 business days*	75.00€
TGM-T6057-25mg	25 mg	7 - 10 business days*	134.00€
TGM-T6057-50mg	50 mg	7 - 10 business days*	219.00€
TGM-T6057-100mg	100 mg	7 - 10 business days*	375.00€

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Description: URMC-099 is an orally bioavailable, brain penetrant MLK inhibitor (IC50:... more

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Product information "URMC-099"

Description: URMC-099 is an orally bioavailable, brain penetrant MLK inhibitor (IC50: 19/42/14/150 nM, for MLK1/MLK2/MLK3/DLK), and also inhibits LRRK2 activity (IC50: 11 nM). Target: Trk receptor, VEGFR, Syk, Autophagy, Src, IGF-1R, Bcr-Abl, CDK, DNA Alkylation, MLK, LRRK2, MEK, Aurora Kinase, SGK, ROCK, c-Met/HGFR. Smiles: CN1CCN(Cc2ccc(cc2)-c2cnc3[nH]cc(-c4ccc5[nH]ccc5c4)c3c2)CC1. References: Goodfellow VS, et al. J Med Chem. 2013, 56(20), 8032-8048.

Supplier:	TargetMol
Supplier-Nr:	T6057

Properties

Application:	MLK inhibitor
MW:	421.54 D
Formula:	C27H27N5

Database Information

CAS :	1229582-33-5\| Matching products
KEGG ID :	K04417 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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