UNC8212

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Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
TGM-T206686-10mg	10 mg	-	-	-	7 - 10 business days*		-
TGM-T206686-50mg	50 mg	-	-	-	7 - 10 business days*		-

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Description: UNC8212 is a potent TAM kinase inhibitor. It exhibits strong inhibitory activity... more

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Product information "UNC8212"

Description: UNC8212 is a potent TAM kinase inhibitor. It exhibits strong inhibitory activity against MERTK and AXL", with IC50 values of 1.5 nM and 1.3 nM, respectively," and also inhibits TYRO3 with an IC50 of 6.7 nM. By targeting the structurally diverse """"back-pocket"""" region within the TAM kinase family"," UNC8212 modulates polypharmacology characteristics. It binds tightly to TAM kinases and effectively inhibits MERTK and AXL phosphorylation. UNC8212 possesses antitumor properties and is applicable in cancer immunotherapy and target studies for tumor cells. Target: TAM Receptor""