TSI-01

Item number	Size	Datasheet	Manual	SDS	Delivery time	Price
TGM-T24904-1mg	1 mg				7 - 10 business days*	70.00€
TGM-T24904-5mg	5 mg				7 - 10 business days*	169.00€
TGM-T24904-1mL	1 ml (1 mL * 10 mM (in DMSO))	-	-	-	7 - 10 business days*	187.00€
TGM-T24904-10mg	10 mg				7 - 10 business days*	295.00€
TGM-T24904-25mg	25 mg				7 - 10 business days*	650.00€
TGM-T24904-50mg	50 mg	-	-	-	7 - 10 business days*	1,032.00€
TGM-T24904-100mg	100 mg	-	-	-	7 - 10 business days*	1,640.00€
TGM-T24904-200mg	200 mg	-	-	-	7 - 10 business days*	2,209.00€

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Description: TSI-01, a pro-inflammatory phospholipid mediator, is rapidly synthesized by lyso-PAF... more

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Product information "TSI-01"

Description: TSI-01, a pro-inflammatory phospholipid mediator, is rapidly synthesized by lyso-PAF acetyltransferase (lyso-PAFAT) in response to extracellular stimuli. Two types of lyso-PAFAT have been identified: LPCAT1, predominantly expressed in lungs, and LPCAT2, expressed in inflammatory cells. TSI-01 is a selective inhibitor of LPCAT2 (IC50 values of 0.47 µM and 3.02 µM for human LPCAT2 and LPCAT1, respectively). At 60 µM, it suppresses PAF biosynthesis in calcium ionophore-stimulated mouse peritoneal macrophages. Target: Others, PAFR. Smiles: O=C(OC(C)C)C1=CC=C(C=C1)N2C(=O)C(Cl)=C(Cl)C2=O

Keywords:	TSI01 , TSI 01
Supplier:	TargetMol
Supplier-Nr:	T24904

Properties

Application:	LPCAT2 inhibitor
MW:	328.15 D
Formula:	C14H11Cl2NO4

Database Information

CAS :	704878-75-1\| Matching products
KEGG ID :	K13510 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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