Trospium-d8 (chloride)

Trospium-d8 is intended for use as an internal standard for the quantification of trospium (Cay-21279) by GC- or LC-MS. Trospium is an antagonist of muscarinic (M) receptors (Kis = 0.50-2.3 nM for human M1-5 recombinant receptors, respectively). Formulations containing antimuscarinics, including trospium, are used to manage overactive bladder by relieving urgency, frequency, and incontinence.Formal Name: (1R,3s,5S)-3-(2-hydroxy-2,2-diphenylacetoxy)spiro[bicyclo[3.2.1]octane-8,1'-pyrrolidin]-8-ium-2',2',3',3',4',4',5',5'-d8, monochloride. Synonyms: Relaspium-d8. Molecular Formula: C25H22D8NO3 . Cl. Formula Weight: 436.0. Purity: >99% deuterated forms (d1-d8). Formulation: (Request formulation change), A solid. Solubility: DMSO: soluble. SMILES: O=C(C(C1=CC=CC=C1)(O)C2=CC=CC=C2)OC3C[C@]([N+]45C([2H])([2H])C([2H])([2H])C([2H])([2H])C4([2H])[2H])([H])CC[C@@]5([H])C3.[Cl-]. InChi Code: InChI=1S/C25H30NO3.ClH/c27-24(25(28,19-9-3-1-4-10-19)20-11-5-2-6-12-20)29-23-17-21-13-14-22(18-23)26(21)15-7-8-16-26,/h1-6,9-12,21-23,28H,7-8,13-18H2,1H/q+1,/p-1/t21-,22-,/m0./s1/i7D2,8D2,15D2,16D2,. InChi Key: RVCSYOQWLPPAOA-ZYIGQORTSA-M.