Trimethylamine N-oxide

Trimethylamine N-oxide
Item number Size Datasheet Manual SDS Delivery time Quantity Price
TGM-T41245-100mg 100 mg

7 - 10 business days*

29.00€
TGM-T41245-1mL 1 ml

7 - 10 business days*

30.00€
 
Description: Trimethylamine N-oxide (TMAO) is a colorless amine oxide produced from choline,... more
Product information "Trimethylamine N-oxide"
Description: Trimethylamine N-oxide (TMAO) is a colorless amine oxide produced from choline, betaine, and carnitine via intestinal microbial metabolism that accumulates in tissues of marine animals and prevents the protein-damaging effects of urea.Trimethylamine N-oxide induces inflammation through activation of ROS/NLRP3 inflammasomes, which can induce fibroblast differentiation and cardiac fibrosis. Target: Reactive Oxygen Species, NOD-like Receptor (NLR), TGF-beta/Smad. Smiles: C[N+](C)(C)[O-]. References: Wei Shuai, et al. High-choline Diet Exacerbates Cardiac Dysfunction, Fibrosis, and Inflammation in a Mouse Model of Heart Failure With Preserved Ejection Fraction. J Card Fail. 2020 May 14,S1071-9164(19)31802-0.
Supplier: TargetMol
Supplier-Nr: T41245

Properties

Application: TMA oxidition FMO4 product, atherosclerosis risk factor
MW: 75.11 D
Formula: C3H9NO

Database Information

CAS : 1184-78-7| Matching products
KEGG ID : K00485 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +4°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H302, H332
P Phrases: P261, P264, P270, P271, P312, P330, P301+P310, P304+P340, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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