Trimethadione

Trimethadione is an anticonvulsant. It decreases the levels of alpha-oxoglutarate, malate, and fumarate in the brain as well as plasma glucose levels in rats. Trimethadione increases latency to first pentetrazole-induced clonic seizure in mice (ED50 = 10 mg/kg). It also inhibits absence-like seizures but not tonic convulsions in spontaneously epileptic rats.Formal Name: 3,5,5-trimethyl-2,4-oxazolidinedione. CAS Number: 127-48-0. Synonyms: NSC 15799, NSC 169503. Molecular Formula: C6H9NO3. Formula Weight: 143.1. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: Chloroform: Slightly Soluble, Methanol: Slightly Soluble. SMILES: O=C(OC1(C)C)N(C)C1=O. InChi Code: InChI=1S/C6H9NO3/c1-6(2)4(8)7(3)5(9)10-6/h1-3H3. InChi Key: IRYJRGCIQBGHIV-UHFFFAOYSA-N.