Trilobatin

Description: Trilobatin (P-Phlorizin) has anti-oxidant effect, can increase superoxide dismutase (SOD) activity.Trilobatin has anti-inflammatory effect, it potentially inhibits the lipopolysaccharide (LPS)-induced inflammatory response by suppressing the NF-kappaB signaling pathway.Trilobatin shows a strong inhibitory activity against alpha-glucosidase and a moderate inhibitory activity against alpha-amylase for management of postprandial hyperglycemia with less side effect. Target: Amylase. Smiles: OC[C@H]1O[C@@H](Oc2cc(O)c(C(=O)CCc3ccc(O)cc3)c(O)c2)[C@H](O)[C@@H](O)[C@@H]1O. References: Fan X , Zhang Y , Dong H , et al. Trilobatin attenuates the LPS-mediated inflammatory response by suppressing the NF-kappaB signaling pathway[J]. Food Chemistry, 2015, 166:609-615.