TPU-0037C

TPU-0037C is a metabolite of the marine actinomycete S. platensis that is structurally similar to lydicamycin (Cay-20584). It is active against Gram-positive bacteria (MICs = 0.39-3.13 µg/ml), including methicillin-resistant S. aureus strains (MIC = 3.13 µg/ml), but is ineffective against Gram-negative bacteria (MICs = >50 µg/ml).Formal Name: (+)-2-[21-[1-[(2,5-dihydro-4-hydroxy-2-oxo-1H-pyrrol-3-yl)carbonyl]-1,2,4a,5,6,7,8,8a-octahydro-5-hydroxy-1,3-dimethyl-2-naphthalenyl]-2,6,10,14,18-pentahydroxy-11,17,19-trimethyl-4,8,12,16-heneicosatetraen-1-yl]-1-pyrrolidinecarboximidamide. CAS Number: 485815-61-0. Molecular Formula: C46H72N4O9. Formula Weight: 825.1. Purity: >95%. Formulation: (Request formulation change), A film. Solubility: DMF: Soluble, DMSO: Soluble, Ethanol: Soluble, Methanol: Soluble. SMILES: OC(C/C=C/C(O)C/C=C/C(O)C(C)/C=C/C(O)C/C=C(C)/C(O)C(CCC1C(C)=CC(C(O)CCC2)C2C1(C)C(C3=C(O)CNC3=O)=O)C)CC4N(C(N)=N)CCC4. InChi Code: InChI=1S/C46H72N4O9/c1-27(38(54)15-7-12-32(51)11-6-13-34(53)25-31-10-9-23-50(31)45(47)48)17-20-33(52)21-18-28(2)42(57)29(3)19-22-36-30(4)24-35-37(14-8-16-39(35)55)46(36,5)43(58)41-40(56)26-49-44(41)59/h6-7,11,15,17-18,20,24,27,29,31-39,42,51-57H,8-10,12-14,16,19,21-23,25-26H2,1-5H3,(H3,47,48)(H,49,59)/b11-6+,15-7+,20-17+,28-18+. InChi Key: UAKZHUQKPSUQEQ-RUKUQFBXSA-N.