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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| Cay27652-5 | 5 mg | - |
6 - 10 business days* |
85.00€
|
|||
| Cay27652-10 | 10 mg | - |
6 - 10 business days* |
149.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
TMCB is a dual inhibitor of casein kinase 2 (CK2) and ERK8 (IC50 = 0.5 µM for both). It also... more
Product information "TMCB"
TMCB is a dual inhibitor of casein kinase 2 (CK2) and ERK8 (IC50 = 0.5 µM for both). It also binds to Pim-1, HIPK2, and DYRK1A (Kis = 8.65, 15.25, and 11.9 µM, respectively) and inhibits greater than 50% of the activity of five kinases, including CK2, ERK8, and DYRK2, in a panel of 78 kinases at 10 µM. TMCB induces apoptosis in Jurkat cells when used at concentrations ranging from 10 to 50 µM.Formal Name: 4,5,6,7-tetrabromo-2-(dimethylamino)-1H-benzimidazole-1-acetic acid. CAS Number: 1085822-09-8. Molecular Formula: C11H9Br4N3O2. Formula Weight: 534.8. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: 25 mM. lambdamax: 240, 274 nm. SMILES: BrC1=C(Br)C(Br)=C(Br)C2=C1N=C(N(C)C)N2CC(O)=O. InChi Code: InChI=1S/C11H9Br4N3O2/c1-17(2)11-16-9-7(14)5(12)6(13)8(15)10(9)18(11)3-4(19)20/h3H2,1-2H3,(H,19,20). InChi Key: PHAOTASRLQMKBE-UHFFFAOYSA-N.
| Keywords: | 4,5,6,7-tetrabromo-2-(dimethylamino)-1H-benzimidazole-1-acetic acid |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 27652 |
Properties
| Application: | CK2 / ERK8 dual inhibitor |
| MW: | 534.8 D |
| Formula: | C11H9Br4N3O2 |
| Purity: | >98% |
| Format: | Crystalline Solid |
Database Information
| CAS : | 1085822-09-8| Matching products |
| KEGG ID : | K19603 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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