TMA-DPH

TMA-DPH is a fluorescent probe for membrane fluidity measurements in artificial and living membrane systems. Acts as an anchor at the lipid/water interface. Specifically and rapidly incorporating into the plasma membrane and between the membranes and the buffer. It is especially useful in the study of monolayer dynamics of lipoproteins and similar analogous systems, exocytosis kinetics and similar systems. TMA-DPH is cylinder-shaped and has fluorescence emission transition dipoles that are basically aligned parallel to its long molecular axis. As such, it is very sensitive to reorientation resulting from interactions with surrounding lipids. TMA-DPH is widely used in fluorescence polarization studies of rotational motion. Spectral Data: lambdaex 355 nm, lambdaem ~430 nm in methanol or DMSO.