Thermopsine

Thermopsine is an alkaloid that has been found in Sophora tonkinensis and has anti-inflammatory activity. It reduces LPS-induced production of TNF-alpha in RAW 264.7 cells when used at a concentration of 50 µM.Formal Name: (7R,14R,14aS)-1,3,4,6,7,13,14,14a-octahydro-7,14-methano-2H,11H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-11-one. CAS Number: 486-90-8. Synonyms: NSC 21725, (-)-Thermopsine. Molecular Formula: C15H20N2O. Formula Weight: 244.3. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: soluble. lambdamax: 234, 311 nm. SMILES: O=C1N(C2=CC=C1)C[C@]3([H])[C@]4([H])CCCCN4C[C@@]2([H])C3. InChi Code: InChI=1S/C15H20N2O/c18-15-6-3-5-14-11-8-12(10-17(14)15)13-4-1-2-7-16(13)9-11/h3,5-6,11-13H,1-2,4,7-10H2/t11-,12-,13+/m1/s1. InChi Key: FQEQMASDZFXSJI-UPJWGTAASA-N. Origin: Plant/Paeonia lactiflora Pall. root.